Mapping of the human COL5A1 gene to chromosome 9q34.3

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A 353-bp region encoding for the NH2 terminus of the noncollagenic part of the αl(V) chain was amplified by the polymerase chain reaction (PCR), subcloned and sequenced. The subcloned PCR product (pGC1) presented the same nucleotide sequence as the original fragment from the published sequence of COL5A1. In situ hybridization, using pGC1 as a probe, mapped the COL5A1 gene to chromosome 9q34.3. This assignement shows that COL5A1 is not synthenic with COL5A2, which is localized together with other collagen genes on chromosome 2.

Original languageEnglish
Pages (from-to)174-176
Number of pages3
JournalHuman Genetics
Issue number1-2
Publication statusPublished - Sep 1992

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics


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