Abstract
The structural gene for β-galactoside-binding protein (Lgals-1), a cell growth regulatory molecule and cystostatic factor, is assigned to the E-region of mouse chromosome 15 and to the region q12-q13.1 of human chromosome 22. The evolutionary conservation of these two regions has been previously suggested from comparative mapping of several loci. These include the murine SIS oncogene (Pdgfb) and its human homolog, the platelet-derived growth factor-β polypeptide, PDGFB. The findings presented here extend the genetic homology of the two regions.
| Original language | English |
|---|---|
| Pages (from-to) | 216-218 |
| Number of pages | 3 |
| Journal | Genomics |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1993 |
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ASJC Scopus subject areas
- Genetics
Cite this
Mapping on Human and Mouse Chromosomes of the Gene for the β-Galactoside-Binding Protein, an Autocrine-Negative Growth Factor. / Baldini, Antonio; Gress, Thomas; Patel, Ketan; Muresu, Rosella; Chiariotti, Lorenzo; Williamson, Penny; Boyd, Yvonne; Casciano, Ida; Wells, Valerie; Bruni, Carmelo B.; Mallucci, Livio; Siniscalco, Marcello.
In: Genomics, Vol. 15, No. 1, 01.1993, p. 216-218.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mapping on Human and Mouse Chromosomes of the Gene for the β-Galactoside-Binding Protein, an Autocrine-Negative Growth Factor
AU - Baldini, Antonio
AU - Gress, Thomas
AU - Patel, Ketan
AU - Muresu, Rosella
AU - Chiariotti, Lorenzo
AU - Williamson, Penny
AU - Boyd, Yvonne
AU - Casciano, Ida
AU - Wells, Valerie
AU - Bruni, Carmelo B.
AU - Mallucci, Livio
AU - Siniscalco, Marcello
PY - 1993/1
Y1 - 1993/1
N2 - The structural gene for β-galactoside-binding protein (Lgals-1), a cell growth regulatory molecule and cystostatic factor, is assigned to the E-region of mouse chromosome 15 and to the region q12-q13.1 of human chromosome 22. The evolutionary conservation of these two regions has been previously suggested from comparative mapping of several loci. These include the murine SIS oncogene (Pdgfb) and its human homolog, the platelet-derived growth factor-β polypeptide, PDGFB. The findings presented here extend the genetic homology of the two regions.
AB - The structural gene for β-galactoside-binding protein (Lgals-1), a cell growth regulatory molecule and cystostatic factor, is assigned to the E-region of mouse chromosome 15 and to the region q12-q13.1 of human chromosome 22. The evolutionary conservation of these two regions has been previously suggested from comparative mapping of several loci. These include the murine SIS oncogene (Pdgfb) and its human homolog, the platelet-derived growth factor-β polypeptide, PDGFB. The findings presented here extend the genetic homology of the two regions.
UR - http://www.scopus.com/inward/record.url?scp=0027447686&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027447686&partnerID=8YFLogxK
U2 - 10.1006/geno.1993.1039
DO - 10.1006/geno.1993.1039
M3 - Article
C2 - 8432540
AN - SCOPUS:0027447686
VL - 15
SP - 216
EP - 218
JO - Genomics
JF - Genomics
SN - 0888-7543
IS - 1
ER -