MARK-AGE standard operating procedures (SOPs): A successful effort

María Moreno-Villanueva, Miriam Capri, Nicolle Breusing, Anne Siepelmeyer, Federica Sevini, Alessandro Ghezzo, Anton J M de Craen, Antti Hervonen, Mikko Hurme, Christiane Schön, Tilman Grune, Claudio Franceschi, Alexander Bürkle

Research output: Contribution to journalArticle


Within the MARK-AGE project, a population study (3337 subjects) was conducted to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any single marker. The MARK-AGE project involves 14 European countries and a total of 26 research centres. In such a study, standard operating procedures (SOPs) are an essential task, which are binding for all MARK-AGE Beneficiaries. The SOPs cover all aspects of subject's recruitment, collection, shipment and distribution of biological samples (blood and its components, buccal mucosa cells or BMC and urine) as well as the anthropometric measurements and questionnaires.

Original languageEnglish
Pages (from-to)18-25
Number of pages8
JournalMechanisms of Ageing and Development
Publication statusPublished - Nov 1 2015


  • Biobank
  • Human studies
  • Standard operating procedures

ASJC Scopus subject areas

  • Ageing
  • Developmental Biology

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    Moreno-Villanueva, M., Capri, M., Breusing, N., Siepelmeyer, A., Sevini, F., Ghezzo, A., de Craen, A. J. M., Hervonen, A., Hurme, M., Schön, C., Grune, T., Franceschi, C., & Bürkle, A. (2015). MARK-AGE standard operating procedures (SOPs): A successful effort. Mechanisms of Ageing and Development, 151, 18-25.