Masked polycythemia Vera (mPV): Results of an international study

Tiziano Barbui, Jürgen Thiele, Heinz Gisslinger, Guido Finazzi, Alessandra Carobbio, Elisa Rumi, Maria Luigia Randi, Irene Betozzi, Alessandro M. Vannucchi, Lisa Pieri, Valentina Carrai, Bettina Gisslinger, Leonhard Müllauer, Marco Ruggeri, Alessandro Rambaldi, Ayalew Tefferi

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

We examined the baseline features and clinical outcomes of 140 patients presenting with JAK2V617F positivity and a bone marrow morphology conforming with WHO criteria of polycythemia vera (PV), but a hemoglobin level of 65 years and leukocyte count >10 × 109/L. Our data suggest that mPV is a heterogeneous myeloproliferative neoplasia and not necessarily an early/ pre-polycythemic form of classical PV that at onset in a small fraction of patients clinically may mimic essential thrombocythemia. On the other hand, the majority mPV may have a longer prodrome of undiagnosed PV or a disease biology akin to primary myelofibrosis-post PV myelofibrosis that could explain the worsening of outcome in comparison to overt/classical manifestations.

Original languageEnglish
Pages (from-to)52-54
Number of pages3
JournalAmerican Journal of Hematology
Volume89
Issue number1
DOIs
Publication statusPublished - Jan 2014

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Polycythemia Vera
Primary Myelofibrosis
Essential Thrombocythemia
Leukocyte Count
Hemoglobins
Bone Marrow
Neoplasms

ASJC Scopus subject areas

  • Hematology

Cite this

Barbui, T., Thiele, J., Gisslinger, H., Finazzi, G., Carobbio, A., Rumi, E., ... Tefferi, A. (2014). Masked polycythemia Vera (mPV): Results of an international study. American Journal of Hematology, 89(1), 52-54. https://doi.org/10.1002/ajh.23585

Masked polycythemia Vera (mPV) : Results of an international study. / Barbui, Tiziano; Thiele, Jürgen; Gisslinger, Heinz; Finazzi, Guido; Carobbio, Alessandra; Rumi, Elisa; Luigia Randi, Maria; Betozzi, Irene; Vannucchi, Alessandro M.; Pieri, Lisa; Carrai, Valentina; Gisslinger, Bettina; Müllauer, Leonhard; Ruggeri, Marco; Rambaldi, Alessandro; Tefferi, Ayalew.

In: American Journal of Hematology, Vol. 89, No. 1, 01.2014, p. 52-54.

Research output: Contribution to journalArticle

Barbui, T, Thiele, J, Gisslinger, H, Finazzi, G, Carobbio, A, Rumi, E, Luigia Randi, M, Betozzi, I, Vannucchi, AM, Pieri, L, Carrai, V, Gisslinger, B, Müllauer, L, Ruggeri, M, Rambaldi, A & Tefferi, A 2014, 'Masked polycythemia Vera (mPV): Results of an international study', American Journal of Hematology, vol. 89, no. 1, pp. 52-54. https://doi.org/10.1002/ajh.23585
Barbui, Tiziano ; Thiele, Jürgen ; Gisslinger, Heinz ; Finazzi, Guido ; Carobbio, Alessandra ; Rumi, Elisa ; Luigia Randi, Maria ; Betozzi, Irene ; Vannucchi, Alessandro M. ; Pieri, Lisa ; Carrai, Valentina ; Gisslinger, Bettina ; Müllauer, Leonhard ; Ruggeri, Marco ; Rambaldi, Alessandro ; Tefferi, Ayalew. / Masked polycythemia Vera (mPV) : Results of an international study. In: American Journal of Hematology. 2014 ; Vol. 89, No. 1. pp. 52-54.
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