Masseter inhibitory reflex in movement disorders. Huntington's chorea, Parkinson's disease, dystonia, and unilateral masticatory spasm

G. Cruccu, G. Pauletti, R. Agostino, A. Berardelli, M. Manfredi

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Evoked by electrical stimulation of the mental nerve, the masseter inhibitory reflex consists of an early and a late silent period (SP1 and SP2), which interrupt the voluntary electromyographic (EMG) activity in the masseter muscle. We recorded the masseter inhibitory reflex and measured its latency, depth of suppression, duration and recovery cycle to paired stimuli, in patients with Huntington's chorea, Parkinson's disease, dystonia, or unilateral masticatory spasm. In patients with Huntington's chorea the reflex data and recovery cycle were normal. In patients with Parkinson's disease or dystonia, although the reflex data were normal, SP2 recovered far more rapidly than it did in control subjects. This is possibly due to hypoactivity of an inhibitory control of the polysynaptic chain of ponto-medullary interneurons that mediate SP2. In patients with unilateral masticatory spasm, both SP1 and SP2 were absent. Suppression is probably absent because this involuntary movement originates at a point along the peripheral course of the nerve.

Original languageEnglish
Pages (from-to)24-30
Number of pages7
JournalElectroencephalography and Clinical Neurophysiology - Evoked Potentials
Volume81
Issue number1
DOIs
Publication statusPublished - 1991

Fingerprint

Dystonia
Huntington Disease
Movement Disorders
Spasm
Parkinson Disease
Reflex
Masseter Muscle
Dyskinesias
Interneurons
Peripheral Nerves
Electric Stimulation

Keywords

  • Dystonia
  • Huntington's chorea
  • Masticatory muscle
  • Parkinson's disease
  • Silent period
  • Trigeminal system

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

@article{8513b6d3d7dc4e9baadf6d32b3562bb7,
title = "Masseter inhibitory reflex in movement disorders. Huntington's chorea, Parkinson's disease, dystonia, and unilateral masticatory spasm",
abstract = "Evoked by electrical stimulation of the mental nerve, the masseter inhibitory reflex consists of an early and a late silent period (SP1 and SP2), which interrupt the voluntary electromyographic (EMG) activity in the masseter muscle. We recorded the masseter inhibitory reflex and measured its latency, depth of suppression, duration and recovery cycle to paired stimuli, in patients with Huntington's chorea, Parkinson's disease, dystonia, or unilateral masticatory spasm. In patients with Huntington's chorea the reflex data and recovery cycle were normal. In patients with Parkinson's disease or dystonia, although the reflex data were normal, SP2 recovered far more rapidly than it did in control subjects. This is possibly due to hypoactivity of an inhibitory control of the polysynaptic chain of ponto-medullary interneurons that mediate SP2. In patients with unilateral masticatory spasm, both SP1 and SP2 were absent. Suppression is probably absent because this involuntary movement originates at a point along the peripheral course of the nerve.",
keywords = "Dystonia, Huntington's chorea, Masticatory muscle, Parkinson's disease, Silent period, Trigeminal system",
author = "G. Cruccu and G. Pauletti and R. Agostino and A. Berardelli and M. Manfredi",
year = "1991",
doi = "10.1016/0168-5597(91)90100-C",
language = "English",
volume = "81",
pages = "24--30",
journal = "Electroencephalography and Clinical Neurophysiology - Evoked Potentials",
issn = "0168-5597",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Masseter inhibitory reflex in movement disorders. Huntington's chorea, Parkinson's disease, dystonia, and unilateral masticatory spasm

AU - Cruccu, G.

AU - Pauletti, G.

AU - Agostino, R.

AU - Berardelli, A.

AU - Manfredi, M.

PY - 1991

Y1 - 1991

N2 - Evoked by electrical stimulation of the mental nerve, the masseter inhibitory reflex consists of an early and a late silent period (SP1 and SP2), which interrupt the voluntary electromyographic (EMG) activity in the masseter muscle. We recorded the masseter inhibitory reflex and measured its latency, depth of suppression, duration and recovery cycle to paired stimuli, in patients with Huntington's chorea, Parkinson's disease, dystonia, or unilateral masticatory spasm. In patients with Huntington's chorea the reflex data and recovery cycle were normal. In patients with Parkinson's disease or dystonia, although the reflex data were normal, SP2 recovered far more rapidly than it did in control subjects. This is possibly due to hypoactivity of an inhibitory control of the polysynaptic chain of ponto-medullary interneurons that mediate SP2. In patients with unilateral masticatory spasm, both SP1 and SP2 were absent. Suppression is probably absent because this involuntary movement originates at a point along the peripheral course of the nerve.

AB - Evoked by electrical stimulation of the mental nerve, the masseter inhibitory reflex consists of an early and a late silent period (SP1 and SP2), which interrupt the voluntary electromyographic (EMG) activity in the masseter muscle. We recorded the masseter inhibitory reflex and measured its latency, depth of suppression, duration and recovery cycle to paired stimuli, in patients with Huntington's chorea, Parkinson's disease, dystonia, or unilateral masticatory spasm. In patients with Huntington's chorea the reflex data and recovery cycle were normal. In patients with Parkinson's disease or dystonia, although the reflex data were normal, SP2 recovered far more rapidly than it did in control subjects. This is possibly due to hypoactivity of an inhibitory control of the polysynaptic chain of ponto-medullary interneurons that mediate SP2. In patients with unilateral masticatory spasm, both SP1 and SP2 were absent. Suppression is probably absent because this involuntary movement originates at a point along the peripheral course of the nerve.

KW - Dystonia

KW - Huntington's chorea

KW - Masticatory muscle

KW - Parkinson's disease

KW - Silent period

KW - Trigeminal system

UR - http://www.scopus.com/inward/record.url?scp=0025762694&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025762694&partnerID=8YFLogxK

U2 - 10.1016/0168-5597(91)90100-C

DO - 10.1016/0168-5597(91)90100-C

M3 - Article

C2 - 1705216

AN - SCOPUS:0025762694

VL - 81

SP - 24

EP - 30

JO - Electroencephalography and Clinical Neurophysiology - Evoked Potentials

JF - Electroencephalography and Clinical Neurophysiology - Evoked Potentials

SN - 0168-5597

IS - 1

ER -