TY - JOUR
T1 - Massive anterior chamber involvement after Intra-arterial chemotherapy for retinoblastoma
T2 - Ultrasound biomicroscopy and histopathology
AU - De Francesco, Sonia
AU - Pichi, Francesco
AU - Lembo, Andrea
AU - Mastrangelo, Domenico
AU - Paradiso, Anna
AU - De Luca, Mariacarla
AU - Toti, Paolo
AU - Nucci, Paolo
AU - Hadjistilianou, Theodora
PY - 2014
Y1 - 2014
N2 - This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance. UBM may represent an important diagnostic tool in retinoblastoma, when the decision about enucleation of the eye must be made in the absence of histopathologic data.
AB - This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance. UBM may represent an important diagnostic tool in retinoblastoma, when the decision about enucleation of the eye must be made in the absence of histopathologic data.
KW - Anterior chamber retinoblastoma
KW - Pseudohypopion
KW - Ultrasound Biomicroscopy
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U2 - 10.1007/s10792-014-9905-0
DO - 10.1007/s10792-014-9905-0
M3 - Article
C2 - 24477744
AN - SCOPUS:84904350011
VL - 34
SP - 967
EP - 970
JO - International Ophthalmology
JF - International Ophthalmology
SN - 0165-5701
IS - 4
ER -