Massive hemobilia and papillomatosis of the gallbladder in metachromatic leukodystrophy: A life-threatening condition

L. Garavelli, S. Rosato, A. Mele, A. Wischmeijer, F. Rivieri, C. Gelmini, F. Sandon, R. Sassatelli, G. Carlinfante, F. Giovanardi, M. Gemmi, E. Della Giustina, S. Amarri, G. Banchini, G. Bedogni

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Polyposis of the gallbladder is rare during childhood. This condition can be associated with three other conditions: metachromatic leukodystrophy, Peutz-Jeghers syndrome, and pancreaticobiliary maljunction. We report the case of a child with hemobilia in metachromatic leukodystrophy, which rendered cholecystectomy necessary. Macroscopically, the gallbladder measured 4.6cm in length and showed an opaque serous surface and focal brown petechiae. Moreover, a yellow polypoid lesion of 2cm in diameter and a diffuse thickening of the fundus wall were observed. Many reports describe the importance of the association of gallbladder papillomatosis with metachromatic leukodystrophy, but only three cases presented with massive intestinal bleeding, such as our young patient had. It is thus imperative that this life-threatening condition should be well known.

Original languageEnglish
Pages (from-to)284-286
Number of pages3
JournalNeuropediatrics
Volume40
Issue number6
DOIs
Publication statusPublished - 2009

Fingerprint

Metachromatic Leukodystrophy
Hemobilia
Papilloma
Gallbladder
Peutz-Jeghers Syndrome
Purpura
Cholecystectomy
Hemorrhage

Keywords

  • gallbladder papillomatosis
  • hemobilia
  • metachromatic leukodystrophy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Garavelli, L., Rosato, S., Mele, A., Wischmeijer, A., Rivieri, F., Gelmini, C., ... Bedogni, G. (2009). Massive hemobilia and papillomatosis of the gallbladder in metachromatic leukodystrophy: A life-threatening condition. Neuropediatrics, 40(6), 284-286. https://doi.org/10.1055/s-0030-1248246

Massive hemobilia and papillomatosis of the gallbladder in metachromatic leukodystrophy : A life-threatening condition. / Garavelli, L.; Rosato, S.; Mele, A.; Wischmeijer, A.; Rivieri, F.; Gelmini, C.; Sandon, F.; Sassatelli, R.; Carlinfante, G.; Giovanardi, F.; Gemmi, M.; Della Giustina, E.; Amarri, S.; Banchini, G.; Bedogni, G.

In: Neuropediatrics, Vol. 40, No. 6, 2009, p. 284-286.

Research output: Contribution to journalArticle

Garavelli, L, Rosato, S, Mele, A, Wischmeijer, A, Rivieri, F, Gelmini, C, Sandon, F, Sassatelli, R, Carlinfante, G, Giovanardi, F, Gemmi, M, Della Giustina, E, Amarri, S, Banchini, G & Bedogni, G 2009, 'Massive hemobilia and papillomatosis of the gallbladder in metachromatic leukodystrophy: A life-threatening condition', Neuropediatrics, vol. 40, no. 6, pp. 284-286. https://doi.org/10.1055/s-0030-1248246
Garavelli, L. ; Rosato, S. ; Mele, A. ; Wischmeijer, A. ; Rivieri, F. ; Gelmini, C. ; Sandon, F. ; Sassatelli, R. ; Carlinfante, G. ; Giovanardi, F. ; Gemmi, M. ; Della Giustina, E. ; Amarri, S. ; Banchini, G. ; Bedogni, G. / Massive hemobilia and papillomatosis of the gallbladder in metachromatic leukodystrophy : A life-threatening condition. In: Neuropediatrics. 2009 ; Vol. 40, No. 6. pp. 284-286.
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