Hémorragie intra-tumorale massive responsable d'un syndrome cave

Une complication rare d'un carcinome hépato-cellulaire

Translated title of the contribution: Massive intrahepatic haemorrhage responsible for an inferior vena cava syndrome: An exceptional complication of hepatocellular carcinoma

Giuseppe Maria Ettorre, Richard Douard, Roberto Santoro, Antonello Vidiri, Giovanni Vennarecci, Fabio Carboni, Arianna Boschetto, Valerio Corazza, Michela Maritti, Mario Antonini, Eugenio Santoro

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Intralesional massive haemorrhage responsible for inferior vena cava syndrome is a very rare complication of hepatocellular carcinoma. A 36-year-old man with no past medical history was referred to hospital for abdominal pain with clinical and biological signs of internal bleeding. An abdominal CT scan showed a huge right liver mass, with regular margins and a fluid content, indicating a large intratumoral haemorrhage complicating hepatocellular carcinoma. Due to haemodynamic stability and the signs of inferior vena cava compression conservative management was chosen prior to surgical treatment of the tumour. Three months later, the huge liver mass remained unchanged but the inferior vena cava syndrome had decreased and the patient's condition improved. After evaluation of liver function and the extent of the tumour, a surgical procedure was performed via a subcostal incision with midline extension and sternotomy to control the intrapericardial inferior vena cava and perform a veno-venous bypass with the technique used for orthotopic liver transplantation. Then, right hepatectomy (segments V to VIII) was performed with an anterior approach. The postoperative course was uneventful. This two-step strategy allowed successful surgery for this rare complication of a hepatocellular carcinoma on a normal liver and could be recommended for the management of any unruptured intratumoral haemorrhages.

Original languageFrench
Pages (from-to)476-479
Number of pages4
JournalGastroenterologie Clinique et Biologique
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 2006

Fingerprint

Inferior Vena Cava
Hepatocellular Carcinoma
Hemorrhage
Liver
Sternotomy
Hepatectomy
Liver Transplantation
Abdominal Pain
Neoplasms
Hemodynamics
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hémorragie intra-tumorale massive responsable d'un syndrome cave : Une complication rare d'un carcinome hépato-cellulaire. / Ettorre, Giuseppe Maria; Douard, Richard; Santoro, Roberto; Vidiri, Antonello; Vennarecci, Giovanni; Carboni, Fabio; Boschetto, Arianna; Corazza, Valerio; Maritti, Michela; Antonini, Mario; Santoro, Eugenio.

In: Gastroenterologie Clinique et Biologique, Vol. 30, No. 3, 03.2006, p. 476-479.

Research output: Contribution to journalArticle

Ettorre, Giuseppe Maria ; Douard, Richard ; Santoro, Roberto ; Vidiri, Antonello ; Vennarecci, Giovanni ; Carboni, Fabio ; Boschetto, Arianna ; Corazza, Valerio ; Maritti, Michela ; Antonini, Mario ; Santoro, Eugenio. / Hémorragie intra-tumorale massive responsable d'un syndrome cave : Une complication rare d'un carcinome hépato-cellulaire. In: Gastroenterologie Clinique et Biologique. 2006 ; Vol. 30, No. 3. pp. 476-479.
@article{73b0ac8861934b0da904bbcf05d09130,
title = "H{\'e}morragie intra-tumorale massive responsable d'un syndrome cave: Une complication rare d'un carcinome h{\'e}pato-cellulaire",
abstract = "Intralesional massive haemorrhage responsible for inferior vena cava syndrome is a very rare complication of hepatocellular carcinoma. A 36-year-old man with no past medical history was referred to hospital for abdominal pain with clinical and biological signs of internal bleeding. An abdominal CT scan showed a huge right liver mass, with regular margins and a fluid content, indicating a large intratumoral haemorrhage complicating hepatocellular carcinoma. Due to haemodynamic stability and the signs of inferior vena cava compression conservative management was chosen prior to surgical treatment of the tumour. Three months later, the huge liver mass remained unchanged but the inferior vena cava syndrome had decreased and the patient's condition improved. After evaluation of liver function and the extent of the tumour, a surgical procedure was performed via a subcostal incision with midline extension and sternotomy to control the intrapericardial inferior vena cava and perform a veno-venous bypass with the technique used for orthotopic liver transplantation. Then, right hepatectomy (segments V to VIII) was performed with an anterior approach. The postoperative course was uneventful. This two-step strategy allowed successful surgery for this rare complication of a hepatocellular carcinoma on a normal liver and could be recommended for the management of any unruptured intratumoral haemorrhages.",
author = "Ettorre, {Giuseppe Maria} and Richard Douard and Roberto Santoro and Antonello Vidiri and Giovanni Vennarecci and Fabio Carboni and Arianna Boschetto and Valerio Corazza and Michela Maritti and Mario Antonini and Eugenio Santoro",
year = "2006",
month = "3",
doi = "10.1016/S0399-8320(06)73207-9",
language = "Francese",
volume = "30",
pages = "476--479",
journal = "Clinics and Research in Hepatology and Gastroenterology",
issn = "2210-7401",
publisher = "Elsevier Masson",
number = "3",

}

TY - JOUR

T1 - Hémorragie intra-tumorale massive responsable d'un syndrome cave

T2 - Une complication rare d'un carcinome hépato-cellulaire

AU - Ettorre, Giuseppe Maria

AU - Douard, Richard

AU - Santoro, Roberto

AU - Vidiri, Antonello

AU - Vennarecci, Giovanni

AU - Carboni, Fabio

AU - Boschetto, Arianna

AU - Corazza, Valerio

AU - Maritti, Michela

AU - Antonini, Mario

AU - Santoro, Eugenio

PY - 2006/3

Y1 - 2006/3

N2 - Intralesional massive haemorrhage responsible for inferior vena cava syndrome is a very rare complication of hepatocellular carcinoma. A 36-year-old man with no past medical history was referred to hospital for abdominal pain with clinical and biological signs of internal bleeding. An abdominal CT scan showed a huge right liver mass, with regular margins and a fluid content, indicating a large intratumoral haemorrhage complicating hepatocellular carcinoma. Due to haemodynamic stability and the signs of inferior vena cava compression conservative management was chosen prior to surgical treatment of the tumour. Three months later, the huge liver mass remained unchanged but the inferior vena cava syndrome had decreased and the patient's condition improved. After evaluation of liver function and the extent of the tumour, a surgical procedure was performed via a subcostal incision with midline extension and sternotomy to control the intrapericardial inferior vena cava and perform a veno-venous bypass with the technique used for orthotopic liver transplantation. Then, right hepatectomy (segments V to VIII) was performed with an anterior approach. The postoperative course was uneventful. This two-step strategy allowed successful surgery for this rare complication of a hepatocellular carcinoma on a normal liver and could be recommended for the management of any unruptured intratumoral haemorrhages.

AB - Intralesional massive haemorrhage responsible for inferior vena cava syndrome is a very rare complication of hepatocellular carcinoma. A 36-year-old man with no past medical history was referred to hospital for abdominal pain with clinical and biological signs of internal bleeding. An abdominal CT scan showed a huge right liver mass, with regular margins and a fluid content, indicating a large intratumoral haemorrhage complicating hepatocellular carcinoma. Due to haemodynamic stability and the signs of inferior vena cava compression conservative management was chosen prior to surgical treatment of the tumour. Three months later, the huge liver mass remained unchanged but the inferior vena cava syndrome had decreased and the patient's condition improved. After evaluation of liver function and the extent of the tumour, a surgical procedure was performed via a subcostal incision with midline extension and sternotomy to control the intrapericardial inferior vena cava and perform a veno-venous bypass with the technique used for orthotopic liver transplantation. Then, right hepatectomy (segments V to VIII) was performed with an anterior approach. The postoperative course was uneventful. This two-step strategy allowed successful surgery for this rare complication of a hepatocellular carcinoma on a normal liver and could be recommended for the management of any unruptured intratumoral haemorrhages.

UR - http://www.scopus.com/inward/record.url?scp=33745785448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745785448&partnerID=8YFLogxK

U2 - 10.1016/S0399-8320(06)73207-9

DO - 10.1016/S0399-8320(06)73207-9

M3 - Articolo

VL - 30

SP - 476

EP - 479

JO - Clinics and Research in Hepatology and Gastroenterology

JF - Clinics and Research in Hepatology and Gastroenterology

SN - 2210-7401

IS - 3

ER -