Massive liver involvement in a patient with multiple myeloma during thalidomide treatment

Research output: Contribution to journalArticle

Abstract

The activity of thalidomide in patients with relapsed or refractory multiple myeloma has been well confirmed. However, plasmacytomas were less responsive to thalidomide and extramedullary progression despite serological response has been observed. We described a case of massive liver involvement in a patient treated with thalidomide; we suggest that extramedullary progression could due to a clone selection induced by treatment.

Original languageEnglish
Pages (from-to)230-232
Number of pages3
JournalHAEMA
Volume6
Issue number2
Publication statusPublished - Apr 2003

Fingerprint

Thalidomide
Multiple Myeloma
Liver
Plasmacytoma
Therapeutics
Clone Cells

Keywords

  • Extramedullary progression
  • Multiple myeloma
  • Thalidomide

ASJC Scopus subject areas

  • Hematology

Cite this

Massive liver involvement in a patient with multiple myeloma during thalidomide treatment. / Nozza, Andrea; Castagna, Luca; Rahal, Daoud; Magagnoli, Massimo; Santoro, Armando.

In: HAEMA, Vol. 6, No. 2, 04.2003, p. 230-232.

Research output: Contribution to journalArticle

@article{f00727ee2c3249e38d0de419c8396e79,
title = "Massive liver involvement in a patient with multiple myeloma during thalidomide treatment",
abstract = "The activity of thalidomide in patients with relapsed or refractory multiple myeloma has been well confirmed. However, plasmacytomas were less responsive to thalidomide and extramedullary progression despite serological response has been observed. We described a case of massive liver involvement in a patient treated with thalidomide; we suggest that extramedullary progression could due to a clone selection induced by treatment.",
keywords = "Extramedullary progression, Multiple myeloma, Thalidomide",
author = "Andrea Nozza and Luca Castagna and Daoud Rahal and Massimo Magagnoli and Armando Santoro",
year = "2003",
month = "4",
language = "English",
volume = "6",
pages = "230--232",
journal = "HAEMA",
issn = "1108-2682",
publisher = "Haema Journal",
number = "2",

}

TY - JOUR

T1 - Massive liver involvement in a patient with multiple myeloma during thalidomide treatment

AU - Nozza, Andrea

AU - Castagna, Luca

AU - Rahal, Daoud

AU - Magagnoli, Massimo

AU - Santoro, Armando

PY - 2003/4

Y1 - 2003/4

N2 - The activity of thalidomide in patients with relapsed or refractory multiple myeloma has been well confirmed. However, plasmacytomas were less responsive to thalidomide and extramedullary progression despite serological response has been observed. We described a case of massive liver involvement in a patient treated with thalidomide; we suggest that extramedullary progression could due to a clone selection induced by treatment.

AB - The activity of thalidomide in patients with relapsed or refractory multiple myeloma has been well confirmed. However, plasmacytomas were less responsive to thalidomide and extramedullary progression despite serological response has been observed. We described a case of massive liver involvement in a patient treated with thalidomide; we suggest that extramedullary progression could due to a clone selection induced by treatment.

KW - Extramedullary progression

KW - Multiple myeloma

KW - Thalidomide

UR - http://www.scopus.com/inward/record.url?scp=0038173638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038173638&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0038173638

VL - 6

SP - 230

EP - 232

JO - HAEMA

JF - HAEMA

SN - 1108-2682

IS - 2

ER -