Mast cell populations in the chick embryo lung and their response to compound 48/80 and dexamethasone

Domenico Ribatti, Renato Contino, Fabio Quondamatteo, Vittoria Formica, Alfredo Tursi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Two mast cell populations, connective tissue mast cells (CTMCs) and mucosal mast cells, (MMCs) containing different proteoglycans in their granules, can be distinguished in several animal species by means of histochemical methods. In this study we documented the presence of these two types of mast cell in the chick embryo lung, from the 15th incubation day for the MMCs, and from the 18th incubation day for the CTMCs. Lungs of embryos treated with compound 48/ 80, which produces degranulation of the CTMCs, showed a decrease in the number of this type of mast cell and an unchanged number of MMCs. In the lungs of embryos treated with dexamethasone, which degranulates MMCs, a reduction in the number of these cells and an unchanged number of the CTMs were found.

Original languageEnglish
Pages (from-to)241-244
Number of pages4
JournalAnatomy and Embryology
Volume186
Issue number3
DOIs
Publication statusPublished - Aug 1992

Fingerprint

p-Methoxy-N-methylphenethylamine
Chick Embryo
Mast Cells
Dexamethasone
Lung
Population
Connective Tissue Cells
Embryonic Structures
Cell Count
Proteoglycans

Keywords

  • Chick
  • Compound 48/80
  • Dexamethasone
  • Lung
  • Mast cell

ASJC Scopus subject areas

  • Embryology
  • Anatomy
  • Developmental Biology
  • Cell Biology

Cite this

Mast cell populations in the chick embryo lung and their response to compound 48/80 and dexamethasone. / Ribatti, Domenico; Contino, Renato; Quondamatteo, Fabio; Formica, Vittoria; Tursi, Alfredo.

In: Anatomy and Embryology, Vol. 186, No. 3, 08.1992, p. 241-244.

Research output: Contribution to journalArticle

Ribatti, D, Contino, R, Quondamatteo, F, Formica, V & Tursi, A 1992, 'Mast cell populations in the chick embryo lung and their response to compound 48/80 and dexamethasone', Anatomy and Embryology, vol. 186, no. 3, pp. 241-244. https://doi.org/10.1007/BF00174145
Ribatti, Domenico ; Contino, Renato ; Quondamatteo, Fabio ; Formica, Vittoria ; Tursi, Alfredo. / Mast cell populations in the chick embryo lung and their response to compound 48/80 and dexamethasone. In: Anatomy and Embryology. 1992 ; Vol. 186, No. 3. pp. 241-244.
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