Abstract
The number of mast cells in the islets of Langerhans in 60 cases was determined in an autopsy study. The 60 patients were divided into 4 groups, distinguishing between those with diabetes, insular amyloidosis, those with both these pathological conditions and those with neither diabetes nor insular amyloidosis. As compared with the control group, it was discovered that there was a sharp increase in mast cells in the group with insular amyloidosis and in the group with diabetes; the number of mast cells tended to increase even more in the presence of both pathological conditions. With these data in hand, it is assumed that the increase in mast cells in the islets of Langerhans is not only due to the presence of amyloidosis, but that it is also brought about as a direct consequence of diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 213-220 |
| Number of pages | 8 |
| Journal | Virchows Archiv A Pathological Anatomy and Histology |
| Volume | 365 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 1975 |
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Keywords
- Aging
- Amyloidosis
- Diabetes Mellitus
- Islets of Langerhans
- Mast Cells
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
- Anatomy
- Medicine(all)
Cite this
Mast cells in the islets of langerhans - A study of their behaviour in connection with diabetes and with insular amyloidosis. / Mlac, M.; Melato, M.; Marin, G.
In: Virchows Archiv A Pathological Anatomy and Histology, Vol. 365, No. 3, 09.1975, p. 213-220.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Mast cells in the islets of langerhans - A study of their behaviour in connection with diabetes and with insular amyloidosis
AU - Mlac, M.
AU - Melato, M.
AU - Marin, G.
PY - 1975/9
Y1 - 1975/9
N2 - The number of mast cells in the islets of Langerhans in 60 cases was determined in an autopsy study. The 60 patients were divided into 4 groups, distinguishing between those with diabetes, insular amyloidosis, those with both these pathological conditions and those with neither diabetes nor insular amyloidosis. As compared with the control group, it was discovered that there was a sharp increase in mast cells in the group with insular amyloidosis and in the group with diabetes; the number of mast cells tended to increase even more in the presence of both pathological conditions. With these data in hand, it is assumed that the increase in mast cells in the islets of Langerhans is not only due to the presence of amyloidosis, but that it is also brought about as a direct consequence of diabetes.
AB - The number of mast cells in the islets of Langerhans in 60 cases was determined in an autopsy study. The 60 patients were divided into 4 groups, distinguishing between those with diabetes, insular amyloidosis, those with both these pathological conditions and those with neither diabetes nor insular amyloidosis. As compared with the control group, it was discovered that there was a sharp increase in mast cells in the group with insular amyloidosis and in the group with diabetes; the number of mast cells tended to increase even more in the presence of both pathological conditions. With these data in hand, it is assumed that the increase in mast cells in the islets of Langerhans is not only due to the presence of amyloidosis, but that it is also brought about as a direct consequence of diabetes.
KW - Aging
KW - Amyloidosis
KW - Diabetes Mellitus
KW - Islets of Langerhans
KW - Mast Cells
UR - http://www.scopus.com/inward/record.url?scp=0016440075&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016440075&partnerID=8YFLogxK
U2 - 10.1007/BF00434040
DO - 10.1007/BF00434040
M3 - Article
C2 - 804751
AN - SCOPUS:0016440075
VL - 365
SP - 213
EP - 220
JO - Virchows Archiv - A Pathological Anatomy and Histopathology
JF - Virchows Archiv - A Pathological Anatomy and Histopathology
SN - 0945-6317
IS - 3
ER -