TY - JOUR
T1 - Maternal high-risk factors and severity of growth deficit in small for gestational age infants
AU - Spinillo, Arsenio
AU - Capuzzo, Ezio
AU - Piazzi, Gaia
AU - Nicola, Sabrina
AU - Colonna, Laura
AU - Iasci, Angela
PY - 1994
Y1 - 1994
N2 - The relationship between maternal risk factors and severity of fetal growth deficit was evaluated in a population of 613 small for gestational age (SGA) infants and 784 appropriately grown controls. The severity of growth deficit among SGA infants was expressed as 'fetal growth ratio' (observed/expected birthweight, where expected birthweight is the mean birth-weight of the Italian population for a given gestational age). In multivariate models, pree-clampsia was the only maternal high-risk factor positively correlated with a more severe growth deficit among SGA infants. Chronic cardiac or renal maternal diseases and female fetal sex were associated with mild forms of SGA, thus showing an inverse relationship with severity of growth deficit. Finally, the association between maternal smoking in pregnancy, low (<0.2 kg/week) maternal weight gain, low (<50 kg) pre-pregnancy weight, severe (Hb, <8 g/dl) maternal anaemia, low education (<6th grade), history of a previous low birth-weight infant or recurrent spontaneous abortion, nulliparity and SGA was homogeneous across the severity strata of fetal growth deficit.
AB - The relationship between maternal risk factors and severity of fetal growth deficit was evaluated in a population of 613 small for gestational age (SGA) infants and 784 appropriately grown controls. The severity of growth deficit among SGA infants was expressed as 'fetal growth ratio' (observed/expected birthweight, where expected birthweight is the mean birth-weight of the Italian population for a given gestational age). In multivariate models, pree-clampsia was the only maternal high-risk factor positively correlated with a more severe growth deficit among SGA infants. Chronic cardiac or renal maternal diseases and female fetal sex were associated with mild forms of SGA, thus showing an inverse relationship with severity of growth deficit. Finally, the association between maternal smoking in pregnancy, low (<0.2 kg/week) maternal weight gain, low (<50 kg) pre-pregnancy weight, severe (Hb, <8 g/dl) maternal anaemia, low education (<6th grade), history of a previous low birth-weight infant or recurrent spontaneous abortion, nulliparity and SGA was homogeneous across the severity strata of fetal growth deficit.
KW - Growth deficit
KW - Risk factors
KW - Small for gestational age
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U2 - 10.1016/0378-3782(94)90048-5
DO - 10.1016/0378-3782(94)90048-5
M3 - Article
C2 - 7982386
AN - SCOPUS:0028023461
VL - 38
SP - 35
EP - 43
JO - Early Human Development
JF - Early Human Development
SN - 0378-3782
IS - 1
ER -