Mating between two balanced translocation carriers in two unrelated families

B. Dallapiccola, L. Chessa, V. Brinchi, M. Frontali, E. Gandini

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Partial trisomy 9p and a 13/14 translocation occurred in the daughter of a t(5;9)(p15;p12) mother and a t(13;14) (p11;q11) father. Two additional offspring displayed a normal karyotype and a translocation trisomy 13 respectively. Two first cousins, selected for chromosome analysis because of a spontaneous abortion, were found to have an identical translocation t(14;21)(p11;q11). Their second pregnancy was monitored by midtrimester amniocentesis and disclosed a balanced fetus. The different zygotic chromosome constitutions and the counselling problems in the marriages between two balanced translocation carriers are discussed.

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalHuman Genetics
Volume65
Issue number2
DOIs
Publication statusPublished - Dec 1983

Fingerprint

Chromosomes
Amniocentesis
Constitution and Bylaws
Second Pregnancy Trimester
Spontaneous Abortion
Marriage
Nuclear Family
Karyotype
Fathers
Counseling
Fetus
Mothers
Pregnancy
Trisomy 13 syndrome
Partial trisomy 9p Chromosome 9

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Mating between two balanced translocation carriers in two unrelated families. / Dallapiccola, B.; Chessa, L.; Brinchi, V.; Frontali, M.; Gandini, E.

In: Human Genetics, Vol. 65, No. 2, 12.1983, p. 165-168.

Research output: Contribution to journalArticle

Dallapiccola, B. ; Chessa, L. ; Brinchi, V. ; Frontali, M. ; Gandini, E. / Mating between two balanced translocation carriers in two unrelated families. In: Human Genetics. 1983 ; Vol. 65, No. 2. pp. 165-168.
@article{abd740144a20498f93cc34a2b9a0acd8,
title = "Mating between two balanced translocation carriers in two unrelated families",
abstract = "Partial trisomy 9p and a 13/14 translocation occurred in the daughter of a t(5;9)(p15;p12) mother and a t(13;14) (p11;q11) father. Two additional offspring displayed a normal karyotype and a translocation trisomy 13 respectively. Two first cousins, selected for chromosome analysis because of a spontaneous abortion, were found to have an identical translocation t(14;21)(p11;q11). Their second pregnancy was monitored by midtrimester amniocentesis and disclosed a balanced fetus. The different zygotic chromosome constitutions and the counselling problems in the marriages between two balanced translocation carriers are discussed.",
author = "B. Dallapiccola and L. Chessa and V. Brinchi and M. Frontali and E. Gandini",
year = "1983",
month = "12",
doi = "10.1007/BF00286655",
language = "English",
volume = "65",
pages = "165--168",
journal = "Human Genetics",
issn = "0340-6717",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Mating between two balanced translocation carriers in two unrelated families

AU - Dallapiccola, B.

AU - Chessa, L.

AU - Brinchi, V.

AU - Frontali, M.

AU - Gandini, E.

PY - 1983/12

Y1 - 1983/12

N2 - Partial trisomy 9p and a 13/14 translocation occurred in the daughter of a t(5;9)(p15;p12) mother and a t(13;14) (p11;q11) father. Two additional offspring displayed a normal karyotype and a translocation trisomy 13 respectively. Two first cousins, selected for chromosome analysis because of a spontaneous abortion, were found to have an identical translocation t(14;21)(p11;q11). Their second pregnancy was monitored by midtrimester amniocentesis and disclosed a balanced fetus. The different zygotic chromosome constitutions and the counselling problems in the marriages between two balanced translocation carriers are discussed.

AB - Partial trisomy 9p and a 13/14 translocation occurred in the daughter of a t(5;9)(p15;p12) mother and a t(13;14) (p11;q11) father. Two additional offspring displayed a normal karyotype and a translocation trisomy 13 respectively. Two first cousins, selected for chromosome analysis because of a spontaneous abortion, were found to have an identical translocation t(14;21)(p11;q11). Their second pregnancy was monitored by midtrimester amniocentesis and disclosed a balanced fetus. The different zygotic chromosome constitutions and the counselling problems in the marriages between two balanced translocation carriers are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0021070666&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021070666&partnerID=8YFLogxK

U2 - 10.1007/BF00286655

DO - 10.1007/BF00286655

M3 - Article

C2 - 6654331

AN - SCOPUS:0021070666

VL - 65

SP - 165

EP - 168

JO - Human Genetics

JF - Human Genetics

SN - 0340-6717

IS - 2

ER -