Abstract
The maturation and release stages of the developmental cycle of a human corona-virus (strain 229 E) in human embryo fibroblast cell cultures were studied by electron microscopy. The maturation takes place by budding of viral components from the limiting membrane of the vesicles of the endoplasmic reticulum. The viral release is usually subsequent to the cell lysis. Neither viral particles into the nucleus, nor budding from the cell membrane were observed. Findings are discussed on the basis of the most recent data of the literature on human and animal coronaviruses.
| Original language | Italian |
|---|---|
| Pages (from-to) | 1121-1124 |
| Number of pages | 4 |
| Journal | Giornale di Malattie Infettive e Parassitarie |
| Volume | 27 |
| Issue number | 12 |
| Publication status | Published - 1975 |
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ASJC Scopus subject areas
- Parasitology
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MATURAZIONE E LIBERAZIONE DI CORONAVIRUS (CEPPO 229 E) IN COLTURE DI FIBROBLASTI EMBRIONALI UMANI. / Gerna, G.; Torsellini Gerna, M.; Gullino, M.; Cereda, P.
In: Giornale di Malattie Infettive e Parassitarie, Vol. 27, No. 12, 1975, p. 1121-1124.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MATURAZIONE E LIBERAZIONE DI CORONAVIRUS (CEPPO 229 E) IN COLTURE DI FIBROBLASTI EMBRIONALI UMANI
AU - Gerna, G.
AU - Torsellini Gerna, M.
AU - Gullino, M.
AU - Cereda, P.
PY - 1975
Y1 - 1975
N2 - The maturation and release stages of the developmental cycle of a human corona-virus (strain 229 E) in human embryo fibroblast cell cultures were studied by electron microscopy. The maturation takes place by budding of viral components from the limiting membrane of the vesicles of the endoplasmic reticulum. The viral release is usually subsequent to the cell lysis. Neither viral particles into the nucleus, nor budding from the cell membrane were observed. Findings are discussed on the basis of the most recent data of the literature on human and animal coronaviruses.
AB - The maturation and release stages of the developmental cycle of a human corona-virus (strain 229 E) in human embryo fibroblast cell cultures were studied by electron microscopy. The maturation takes place by budding of viral components from the limiting membrane of the vesicles of the endoplasmic reticulum. The viral release is usually subsequent to the cell lysis. Neither viral particles into the nucleus, nor budding from the cell membrane were observed. Findings are discussed on the basis of the most recent data of the literature on human and animal coronaviruses.
UR - http://www.scopus.com/inward/record.url?scp=0016785221&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016785221&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0016785221
VL - 27
SP - 1121
EP - 1124
JO - Giornale di Malattie Infettive e Parassitarie
JF - Giornale di Malattie Infettive e Parassitarie
SN - 0017-0321
IS - 12
ER -