MATURAZIONE E LIBERAZIONE DI CORONAVIRUS (CEPPO 229 E) IN COLTURE DI FIBROBLASTI EMBRIONALI UMANI

Translated title of the contribution: Maturation and release of coronavirus (229 E strain) in human embryo fibroblast cell cultures

G. Gerna, M. Torsellini Gerna, M. Gullino, P. Cereda

Research output: Contribution to journalArticle

Abstract

The maturation and release stages of the developmental cycle of a human corona-virus (strain 229 E) in human embryo fibroblast cell cultures were studied by electron microscopy. The maturation takes place by budding of viral components from the limiting membrane of the vesicles of the endoplasmic reticulum. The viral release is usually subsequent to the cell lysis. Neither viral particles into the nucleus, nor budding from the cell membrane were observed. Findings are discussed on the basis of the most recent data of the literature on human and animal coronaviruses.

Original languageItalian
Pages (from-to)1121-1124
Number of pages4
JournalGiornale di Malattie Infettive e Parassitarie
Volume27
Issue number12
Publication statusPublished - 1975

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Coronavirus
Embryonic Structures
Cell Culture Techniques
Fibroblasts
Viral Structures
Endoplasmic Reticulum
Virion
Electron Microscopy
Cell Membrane
Viruses
Membranes

ASJC Scopus subject areas

  • Parasitology

Cite this

MATURAZIONE E LIBERAZIONE DI CORONAVIRUS (CEPPO 229 E) IN COLTURE DI FIBROBLASTI EMBRIONALI UMANI. / Gerna, G.; Torsellini Gerna, M.; Gullino, M.; Cereda, P.

In: Giornale di Malattie Infettive e Parassitarie, Vol. 27, No. 12, 1975, p. 1121-1124.

Research output: Contribution to journalArticle

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