MATURAZIONE E LIBERAZIONE DI CORONAVIRUS (CEPPO 229 E) IN COLTURE DI FIBROBLASTI EMBRIONALI UMANI

Translated title of the contribution: Maturation and release of coronavirus (229 E strain) in human embryo fibroblast cell cultures

G. Gerna, M. Torsellini Gerna, M. Gullino, P. Cereda

Research output: Contribution to journalArticlepeer-review

Abstract

The maturation and release stages of the developmental cycle of a human corona-virus (strain 229 E) in human embryo fibroblast cell cultures were studied by electron microscopy. The maturation takes place by budding of viral components from the limiting membrane of the vesicles of the endoplasmic reticulum. The viral release is usually subsequent to the cell lysis. Neither viral particles into the nucleus, nor budding from the cell membrane were observed. Findings are discussed on the basis of the most recent data of the literature on human and animal coronaviruses.

Translated title of the contributionMaturation and release of coronavirus (229 E strain) in human embryo fibroblast cell cultures
Original languageItalian
Pages (from-to)1121-1124
Number of pages4
JournalGiornale di Malattie Infettive e Parassitarie
Volume27
Issue number12
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Parasitology

Fingerprint Dive into the research topics of 'Maturation and release of coronavirus (229 E strain) in human embryo fibroblast cell cultures'. Together they form a unique fingerprint.

Cite this