Abstract
Processing speed is a frequently affected cognitive domain in pediatric multiple sclerosis (MS) and is commonly assessed using the Symbol Digit Modalities Test (SDMT). The objective of this study was to determine maturational trajectories in SDMT performance and baseline factors affecting trajectories in a sample of 82 pediatric MS individuals. Performance on the SDMT increased with age in patients with pediatric MS followed by a subsequent decline. Furthermore, patients who were older at disease onset and had a higher IQ showed greater gains with age, suggesting that these factors may be protective with respect to cognitive maturation in pediatric MS.
| Original language | English |
|---|---|
| Pages (from-to) | 299-308 |
| Number of pages | 10 |
| Journal | Developmental Neuropsychology |
| Volume | 42 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jul 4 2017 |
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ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Developmental and Educational Psychology
Cite this
Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis. / Akbar, Nadine; Signori, Alessio; Amato, Maria Pia; Sormani, Maria Pia; Portaccio, Emilio; Niccolai, Claudia; Goretti, Benedetta; Till, Christine; Banwell, Brenda.
In: Developmental Neuropsychology, Vol. 42, No. 5, 04.07.2017, p. 299-308.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis
AU - Akbar, Nadine
AU - Signori, Alessio
AU - Amato, Maria Pia
AU - Sormani, Maria Pia
AU - Portaccio, Emilio
AU - Niccolai, Claudia
AU - Goretti, Benedetta
AU - Till, Christine
AU - Banwell, Brenda
PY - 2017/7/4
Y1 - 2017/7/4
N2 - Processing speed is a frequently affected cognitive domain in pediatric multiple sclerosis (MS) and is commonly assessed using the Symbol Digit Modalities Test (SDMT). The objective of this study was to determine maturational trajectories in SDMT performance and baseline factors affecting trajectories in a sample of 82 pediatric MS individuals. Performance on the SDMT increased with age in patients with pediatric MS followed by a subsequent decline. Furthermore, patients who were older at disease onset and had a higher IQ showed greater gains with age, suggesting that these factors may be protective with respect to cognitive maturation in pediatric MS.
AB - Processing speed is a frequently affected cognitive domain in pediatric multiple sclerosis (MS) and is commonly assessed using the Symbol Digit Modalities Test (SDMT). The objective of this study was to determine maturational trajectories in SDMT performance and baseline factors affecting trajectories in a sample of 82 pediatric MS individuals. Performance on the SDMT increased with age in patients with pediatric MS followed by a subsequent decline. Furthermore, patients who were older at disease onset and had a higher IQ showed greater gains with age, suggesting that these factors may be protective with respect to cognitive maturation in pediatric MS.
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U2 - 10.1080/87565641.2017.1351974
DO - 10.1080/87565641.2017.1351974
M3 - Article
VL - 42
SP - 299
EP - 308
JO - Developmental Neuropsychology
JF - Developmental Neuropsychology
SN - 8756-5641
IS - 5
ER -