Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis

Nadine Akbar, Alessio Signori, Maria Pia Amato, Maria Pia Sormani, Emilio Portaccio, Claudia Niccolai, Benedetta Goretti, Christine Till, Brenda Banwell

Research output: Contribution to journalArticle

Abstract

Processing speed is a frequently affected cognitive domain in pediatric multiple sclerosis (MS) and is commonly assessed using the Symbol Digit Modalities Test (SDMT). The objective of this study was to determine maturational trajectories in SDMT performance and baseline factors affecting trajectories in a sample of 82 pediatric MS individuals. Performance on the SDMT increased with age in patients with pediatric MS followed by a subsequent decline. Furthermore, patients who were older at disease onset and had a higher IQ showed greater gains with age, suggesting that these factors may be protective with respect to cognitive maturation in pediatric MS.

Original languageEnglish
Pages (from-to)299-308
Number of pages10
JournalDevelopmental Neuropsychology
Volume42
Issue number5
DOIs
Publication statusPublished - Jul 4 2017

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology

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    Akbar, N., Signori, A., Amato, M. P., Sormani, M. P., Portaccio, E., Niccolai, C., Goretti, B., Till, C., & Banwell, B. (2017). Maturational Trajectory of Processing Speed Performance in Pediatric Multiple Sclerosis. Developmental Neuropsychology, 42(5), 299-308. https://doi.org/10.1080/87565641.2017.1351974