Maturity-onset diabetes of the young with necrobiosis lipoidica and granuloma annulare

Federico Marchetti, Tania Gerarduzzi, Filippo Longo, Elena Faleschini, Alessandro Ventura, Giorgio Tonini

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We describe a 12-year-old white girl with granuloma annulare localized to both ankles since she was five, necrobiosis lipoidica in the left pretibial region since she was ten, and a recent history of weakness, migraine, and weight loss. After initial evaluation, high fasting blood glucose levels and high hemoglobin A1c were found. The family history for non-insulin-dependent diabetes was suggestive of maturity-onset diabetes of the young. Coexistence of necrobiosis lipoidica and granuloma annulare, together with a family history of non-insulin-dependent diabetes, the age of onset, and the absence of ketosis, are specific features making possible, a clinical diagnosis. Genetic confirmation may not be so easily accessible or necessary.

Original languageEnglish
Pages (from-to)247-250
Number of pages4
JournalPediatric Dermatology
Issue number3
Publication statusPublished - May 2006

ASJC Scopus subject areas

  • Dermatology
  • Pediatrics, Perinatology, and Child Health


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