Maxillary Sinus Floor Augmentation Using Biphasic Calcium Phosphate and a Hydrogel Polyethylene Glycol Covering Membrane: An Histological and Histomorphometric Evaluation

Laurent Ohayon, Silvio Taschieri, Stefano Corbella, Massimo Del Fabbro

Research output: Contribution to journalArticle

Abstract

PURPOSE:: Maxillary sinus floor augmentation with a lateral approach is usually performed using a bone substitute covered with standard collagen or a synthetic barrier membrane to prevent soft tissue ingrowth within the bone graft. The purpose of this case series was to evaluate a polyethylene glycol (PEG) membrane with a hydrogel consistency, used to protect the lateral sinus anstrotomy, by analyzing the histological quality and histomorphometric quantity of newly formed bone (NB) in a maxillary sinus graft using biphasic calcium phosphate (BCP). MATERIALS AND METHODS:: Fifteen sinuses were grafted from 12 patients. Six months after the maxillary sinus floor augmentation, bone biopsies were harvested from 7 patients during the implant placement second-step surgery. RESULTS:: The histomorphometric evaluation of the 7 grafted sinuses showed mean values of 27.4 ± 4.6% for NB, 26.9 ± 5.4% for remaining BCP particles, and 45.7 ± 6.0% for connective tissue/bone marrow. No implant failure was observed in the 14- to 45-month follow-up period after maxillary sinus floor augmentation procedure and in the 8- to 39-month follow-up period after implant loading. CONCLUSION:: The use of a hydrogel PEG membrane to protect BCP proved to be a valuable grafting procedure to enhance the vital bone formation in the maxillary sinus floor augmentation procedure.

Original languageEnglish
JournalImplant Dentistry
DOIs
Publication statusAccepted/In press - Aug 2 2016

Fingerprint

Sinus Floor Augmentation
Hydrogel
Bone and Bones
Membranes
Transverse Sinuses
Transplants
Bone Substitutes
Maxillary Sinus
Osteogenesis
Connective Tissue
Collagen
Bone Marrow
Biopsy
hydroxyapatite-beta tricalcium phosphate

ASJC Scopus subject areas

  • Oral Surgery

Cite this

@article{db1822faf643446cbe9fe98815186377,
title = "Maxillary Sinus Floor Augmentation Using Biphasic Calcium Phosphate and a Hydrogel Polyethylene Glycol Covering Membrane: An Histological and Histomorphometric Evaluation",
abstract = "PURPOSE:: Maxillary sinus floor augmentation with a lateral approach is usually performed using a bone substitute covered with standard collagen or a synthetic barrier membrane to prevent soft tissue ingrowth within the bone graft. The purpose of this case series was to evaluate a polyethylene glycol (PEG) membrane with a hydrogel consistency, used to protect the lateral sinus anstrotomy, by analyzing the histological quality and histomorphometric quantity of newly formed bone (NB) in a maxillary sinus graft using biphasic calcium phosphate (BCP). MATERIALS AND METHODS:: Fifteen sinuses were grafted from 12 patients. Six months after the maxillary sinus floor augmentation, bone biopsies were harvested from 7 patients during the implant placement second-step surgery. RESULTS:: The histomorphometric evaluation of the 7 grafted sinuses showed mean values of 27.4 ± 4.6{\%} for NB, 26.9 ± 5.4{\%} for remaining BCP particles, and 45.7 ± 6.0{\%} for connective tissue/bone marrow. No implant failure was observed in the 14- to 45-month follow-up period after maxillary sinus floor augmentation procedure and in the 8- to 39-month follow-up period after implant loading. CONCLUSION:: The use of a hydrogel PEG membrane to protect BCP proved to be a valuable grafting procedure to enhance the vital bone formation in the maxillary sinus floor augmentation procedure.",
author = "Laurent Ohayon and Silvio Taschieri and Stefano Corbella and {Del Fabbro}, Massimo",
year = "2016",
month = "8",
day = "2",
doi = "10.1097/ID.0000000000000435",
language = "English",
journal = "Implant Dentistry",
issn = "1056-6163",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Maxillary Sinus Floor Augmentation Using Biphasic Calcium Phosphate and a Hydrogel Polyethylene Glycol Covering Membrane

T2 - An Histological and Histomorphometric Evaluation

AU - Ohayon, Laurent

AU - Taschieri, Silvio

AU - Corbella, Stefano

AU - Del Fabbro, Massimo

PY - 2016/8/2

Y1 - 2016/8/2

N2 - PURPOSE:: Maxillary sinus floor augmentation with a lateral approach is usually performed using a bone substitute covered with standard collagen or a synthetic barrier membrane to prevent soft tissue ingrowth within the bone graft. The purpose of this case series was to evaluate a polyethylene glycol (PEG) membrane with a hydrogel consistency, used to protect the lateral sinus anstrotomy, by analyzing the histological quality and histomorphometric quantity of newly formed bone (NB) in a maxillary sinus graft using biphasic calcium phosphate (BCP). MATERIALS AND METHODS:: Fifteen sinuses were grafted from 12 patients. Six months after the maxillary sinus floor augmentation, bone biopsies were harvested from 7 patients during the implant placement second-step surgery. RESULTS:: The histomorphometric evaluation of the 7 grafted sinuses showed mean values of 27.4 ± 4.6% for NB, 26.9 ± 5.4% for remaining BCP particles, and 45.7 ± 6.0% for connective tissue/bone marrow. No implant failure was observed in the 14- to 45-month follow-up period after maxillary sinus floor augmentation procedure and in the 8- to 39-month follow-up period after implant loading. CONCLUSION:: The use of a hydrogel PEG membrane to protect BCP proved to be a valuable grafting procedure to enhance the vital bone formation in the maxillary sinus floor augmentation procedure.

AB - PURPOSE:: Maxillary sinus floor augmentation with a lateral approach is usually performed using a bone substitute covered with standard collagen or a synthetic barrier membrane to prevent soft tissue ingrowth within the bone graft. The purpose of this case series was to evaluate a polyethylene glycol (PEG) membrane with a hydrogel consistency, used to protect the lateral sinus anstrotomy, by analyzing the histological quality and histomorphometric quantity of newly formed bone (NB) in a maxillary sinus graft using biphasic calcium phosphate (BCP). MATERIALS AND METHODS:: Fifteen sinuses were grafted from 12 patients. Six months after the maxillary sinus floor augmentation, bone biopsies were harvested from 7 patients during the implant placement second-step surgery. RESULTS:: The histomorphometric evaluation of the 7 grafted sinuses showed mean values of 27.4 ± 4.6% for NB, 26.9 ± 5.4% for remaining BCP particles, and 45.7 ± 6.0% for connective tissue/bone marrow. No implant failure was observed in the 14- to 45-month follow-up period after maxillary sinus floor augmentation procedure and in the 8- to 39-month follow-up period after implant loading. CONCLUSION:: The use of a hydrogel PEG membrane to protect BCP proved to be a valuable grafting procedure to enhance the vital bone formation in the maxillary sinus floor augmentation procedure.

UR - http://www.scopus.com/inward/record.url?scp=84983528613&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84983528613&partnerID=8YFLogxK

U2 - 10.1097/ID.0000000000000435

DO - 10.1097/ID.0000000000000435

M3 - Article

AN - SCOPUS:84983528613

JO - Implant Dentistry

JF - Implant Dentistry

SN - 1056-6163

ER -