Maxillary Sinus Grafting with Biphasic Bone Ceramic or Autogenous Bone: Clinical, Histologic, and Histomorphometric Results from a Randomized Controlled Clinical Trial

Seyed A. Danesh-Sani, Stephen S. Wallace, Ali Movahed, Edgard S. El Chaar, Sang Choon Cho, Ismael Khouly, Tiziano Testori

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: The present, randomized, controlled clinical trial compared the histologic and histomorphometric results from maxillary sinus augmentation with either biphasic calcium phosphate (BCP) (60% hydroxyapatite and 40% β-tricalcium phosphate) or autogenous bone (AB) as bone-grafting materials. Material and Methods: Ten patients received bilateral sinus elevation surgery with intraoral AB chips (control group) on one side and BCP (test group) on the contralateral side. After a healing period of 6 to 8 months, implant sites were created and trephine cores were harvested for histological and histomorphometric analysis of the grafted areas. Results: The histological examination of biopsies showed BCP particles interconnected by bridges of a vital newly formed bone. Histomorphometry demonstrated that the amount of newly formed bone in the control group (36.8%) was significantly greater than that in the BCP (28.2%) group (P 0.0032). BCP and AB cores revealed an average of residual graft particles of 32.9% and 4.8%, respectively. The average percentage of soft tissue components was 38.9% in the BCP cores and 58.4% in the AB cores. Conclusions: Based on our findings, the amount of vital bone formation was significantly higher for AB than that for BCP. However, BCP seemed to be a biocompatible and osteoconductive material that can be used with success as a bone substitute in maxillary sinus procedures.

Original languageEnglish
Pages (from-to)588-593
Number of pages6
JournalImplant Dentistry
Volume25
Issue number5
DOIs
Publication statusPublished - Oct 1 2016
Externally publishedYes

Fingerprint

Maxillary Sinus
Ceramics
Randomized Controlled Trials
Bone and Bones
Bone Substitutes
Control Groups
Bone Transplantation
hydroxyapatite-beta tricalcium phosphate
Biocompatible Materials
Durapatite
Osteogenesis
Transplants
Biopsy

Keywords

  • autogenous bone sinus augmentation
  • biphasic calcium phosphate
  • bone substitute
  • sinus floor elevation

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Maxillary Sinus Grafting with Biphasic Bone Ceramic or Autogenous Bone : Clinical, Histologic, and Histomorphometric Results from a Randomized Controlled Clinical Trial. / Danesh-Sani, Seyed A.; Wallace, Stephen S.; Movahed, Ali; El Chaar, Edgard S.; Cho, Sang Choon; Khouly, Ismael; Testori, Tiziano.

In: Implant Dentistry, Vol. 25, No. 5, 01.10.2016, p. 588-593.

Research output: Contribution to journalArticle

Danesh-Sani, Seyed A. ; Wallace, Stephen S. ; Movahed, Ali ; El Chaar, Edgard S. ; Cho, Sang Choon ; Khouly, Ismael ; Testori, Tiziano. / Maxillary Sinus Grafting with Biphasic Bone Ceramic or Autogenous Bone : Clinical, Histologic, and Histomorphometric Results from a Randomized Controlled Clinical Trial. In: Implant Dentistry. 2016 ; Vol. 25, No. 5. pp. 588-593.
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