Abstract
We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.
Original language | English |
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Pages (from-to) | 189-191 |
Number of pages | 3 |
Journal | Journal of Cystic Fibrosis |
Volume | 4 |
Issue number | 3 |
DOIs | |
Publication status | Published - Sep 2005 |
Keywords
- Cystic fibrosis
- Mannose-binding lectin
- MBL2
- Modifier genes
- Respiratory infections
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine