MBL2 polymorphisms screening in a regional Italian CF Center

Chiara Trevisiol; Michele Boniotto; Luisella Giglio; Furio Poli; Marcello Morgutti; Sergio Crovella

doi:10.1016/j.jcf.2005.04.001

MBL2 polymorphisms screening in a regional Italian CF Center

Chiara Trevisiol, Michele Boniotto, Luisella Giglio, Furio Poli, Marcello Morgutti, Sergio Crovella

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.

Original language	English
Pages (from-to)	189-191
Number of pages	3
Journal	Journal of Cystic Fibrosis
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/j.jcf.2005.04.001
Publication status	Published - Sep 2005

Keywords

Cystic fibrosis
Mannose-binding lectin
MBL2
Modifier genes
Respiratory infections

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.jcf.2005.04.001

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title = "MBL2 polymorphisms screening in a regional Italian CF Center",

abstract = "We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.",

keywords = "Cystic fibrosis, Mannose-binding lectin, MBL2, Modifier genes, Respiratory infections",

author = "Chiara Trevisiol and Michele Boniotto and Luisella Giglio and Furio Poli and Marcello Morgutti and Sergio Crovella",

year = "2005",

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AU - Trevisiol, Chiara

AU - Boniotto, Michele

AU - Giglio, Luisella

AU - Poli, Furio

AU - Morgutti, Marcello

AU - Crovella, Sergio

PY - 2005/9

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N2 - We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.

AB - We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.

KW - Cystic fibrosis

KW - Mannose-binding lectin

KW - MBL2

KW - Modifier genes

KW - Respiratory infections

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MBL2 polymorphisms screening in a regional Italian CF Center

Abstract

Keywords

ASJC Scopus subject areas

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