MBL2 polymorphisms screening in a regional Italian CF Center

Chiara Trevisiol, Michele Boniotto, Luisella Giglio, Furio Poli, Marcello Morgutti, Sergio Crovella

Research output: Contribution to journalArticlepeer-review


We performed MBL2 genotyping in 47 CF patients - cared of at the regional CF Centre of Trieste - trying to establish a correlation within allelic variants of MBL2 and modification of patients' clinical outcome. FEV1 values were significantly lowered and a significantly earlier age at onset of Pseudomonas aeruginosa colonisation was found in CF patients with at least one MBL2 variant.

Original languageEnglish
Pages (from-to)189-191
Number of pages3
JournalJournal of Cystic Fibrosis
Issue number3
Publication statusPublished - Sep 2005


  • Cystic fibrosis
  • Mannose-binding lectin
  • MBL2
  • Modifier genes
  • Respiratory infections

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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