Measurement agreement between a new biometer based on partial coherence interferometry and a validated biometer based on optical low-coherence reflectometry

Junhua Li, Hao Chen, Giacomo Savini, Weicong Lu, Xinxin Yu, Fangjun Bao, Qinmei Wang, Jinhai Huang

Research output: Contribution to journalArticle

Abstract

Purpose To evaluate the agreement of ocular measurements obtained with a new optical biometer (AL-Scan) and a previously validated optical biometer (Lenstar). Setting Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. Design Prospective observational cross-sectional study. Methods For a comprehensive comparison between the partial coherence interferometry (PCI) device and the optical low-coherence reflectometry (OLCR) device, the axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, mean keratometry (K), astigmatism, white-to-white (WTW), and pupil diameter were measured 3 times per device in eyes with cataract. The sequence of the device was in random order. The mean values were compared and 95% limits of agreement (LoA) were assessed. Results Ninety-two eyes of 92 cataract patients were included. Bland-Altman analysis showed excellent agreement between the PCI device and the OLCR device for AL, CCT, ACD and aqueous depth measurements with narrow 95% LoA (-0.05 to 0.06 mm, -13.39 to 15.61 μm, -0.11 to 0.10 mm, and -0.12 to 0.10 mm, respectively), and the P values were more than 0.05. The mean K, astigmatism, and WTW values provided by the PCI device were in good agreement with the OLCR device, although statistically significant differences were detected. A major difference was observed in the pupil diameter measurement, with a 95% LoA of -0.73 to 1.21 mm. Conclusions The PCI device biometer provided ocular measurements similar to those provided by the OLCR device for most parameters, especially for AL, CCT, and ACD. The pupil diameter values obtained with the PCI device were in poor agreement with the OLCR device, and these measurements should be interpreted with necessary adjustment. Financial Disclosure None of the authors has a proprietary or financial interest in any material or method mentioned.

Original languageEnglish
Pages (from-to)68-75
Number of pages8
JournalJournal of Cataract and Refractive Surgery
Volume42
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Surgery

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