Measurement of lipocalin-2 and syndecan-4 levels to differentiate bacterial from viral infection in children with community-acquired pneumonia

Susanna Esposito, Sonia Bianchini, Monia Gambino, Barbara Madini, Giada Di Pietro, Giulia Umbrello, Maria Lory Presicce, Luca Ruggiero, Leonardo Terranova, Nicola Principi

Research output: Contribution to journalArticle

Abstract

Background: In this study, we evaluated the lipocalin-2 (LIP2) and syndecan-4 (SYN4) levels in children who were hospitalized for radiologically confirmed CAP in order to differentiate bacterial from viral infection. The results regarding the LIP2 and SYN4 diagnostic outcomes were compared with the white blood cell (WBC) count and C reactive protein (CRP) levels. Methods: A total of 110 children

Original languageEnglish
Article number103
JournalBMC Pulmonary Medicine
Volume16
Issue number1
DOIs
Publication statusPublished - Jul 20 2016

Keywords

  • Biomarkers
  • C reactive protein
  • Community-acquired pneumonia
  • Lipocalin 2
  • Syndecan 4
  • White blood cell count

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Esposito, S., Bianchini, S., Gambino, M., Madini, B., Di Pietro, G., Umbrello, G., Presicce, M. L., Ruggiero, L., Terranova, L., & Principi, N. (2016). Measurement of lipocalin-2 and syndecan-4 levels to differentiate bacterial from viral infection in children with community-acquired pneumonia. BMC Pulmonary Medicine, 16(1), [103]. https://doi.org/10.1186/s12890-016-0267-4