Mechanical thrombectomy of acute ischemic stroke with a new intermediate aspiration catheter

Preliminary results

Fabrizio Sallustio, Enrico Pampana, Alessandro Davoli, Stefano Merolla, Giacomo Koch, Fana Alemseged, Marta Panella, Vittoria Carla D'Agostino, Francesco Mori, Daniele Morosetti, Daniel Konda, Sebastiano Fabiano, Marina Diomedi, Roberto Gandini

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background and purpose: To report clinical and procedural outcomes of acute ischemic stroke patients after endovascular treatment with the new thromboaspiration catheter AXS Catalyst 6. Methods: Patients with anterior and posterior circulation stroke were selected. Successful reperfusion defined as a Thrombolysis in Cerebral Infarction (TICI) score ≥2 b and 3-month functional independence defined as a modified Rankin Scale (mRS) ≤2 were the main efficacy outcomes. Symptomatic intracranial hemorrhage and mortality were the main safety outcomes. Results: 107 patients were suitable for analysis. Mean age was 73.18±12.62 year and median baseline NIHSS was 17 (range: 3-32). The most frequent site of occlusion was the middle cerebral artery (MCA) (60.7%). 76.6% of patients were treated with AXS Catalyst 6 alone without the need for rescue devices or thromboaspiration catheters. Successful reperfusion was achieved in 84.1%, functional independence in 47.6%, symptomatic intracranial hemorrhage occurred in 3.7%, and mortality in 21.4%. Conclusions: Endovascular treatment with AXS Catalyst 6 proved to be safe, technically feasible, and effective. Comparison analyses with other devices for mechanical thrombectomy are needed.

Original languageEnglish
JournalJournal of NeuroInterventional Surgery
DOIs
Publication statusAccepted/In press - Feb 8 2018

Fingerprint

Thrombectomy
Catheters
Stroke
Intracranial Hemorrhages
Reperfusion
Equipment and Supplies
Mortality
Middle Cerebral Artery Infarction
Cerebral Infarction
Safety
Therapeutics

Keywords

  • catheter
  • device
  • stroke
  • thrombectomy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Mechanical thrombectomy of acute ischemic stroke with a new intermediate aspiration catheter : Preliminary results. / Sallustio, Fabrizio; Pampana, Enrico; Davoli, Alessandro; Merolla, Stefano; Koch, Giacomo; Alemseged, Fana; Panella, Marta; D'Agostino, Vittoria Carla; Mori, Francesco; Morosetti, Daniele; Konda, Daniel; Fabiano, Sebastiano; Diomedi, Marina; Gandini, Roberto.

In: Journal of NeuroInterventional Surgery, 08.02.2018.

Research output: Contribution to journalArticle

Sallustio, F, Pampana, E, Davoli, A, Merolla, S, Koch, G, Alemseged, F, Panella, M, D'Agostino, VC, Mori, F, Morosetti, D, Konda, D, Fabiano, S, Diomedi, M & Gandini, R 2018, 'Mechanical thrombectomy of acute ischemic stroke with a new intermediate aspiration catheter: Preliminary results', Journal of NeuroInterventional Surgery. https://doi.org/10.1136/neurintsurg-2017-013679
Sallustio, Fabrizio ; Pampana, Enrico ; Davoli, Alessandro ; Merolla, Stefano ; Koch, Giacomo ; Alemseged, Fana ; Panella, Marta ; D'Agostino, Vittoria Carla ; Mori, Francesco ; Morosetti, Daniele ; Konda, Daniel ; Fabiano, Sebastiano ; Diomedi, Marina ; Gandini, Roberto. / Mechanical thrombectomy of acute ischemic stroke with a new intermediate aspiration catheter : Preliminary results. In: Journal of NeuroInterventional Surgery. 2018.
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abstract = "Background and purpose: To report clinical and procedural outcomes of acute ischemic stroke patients after endovascular treatment with the new thromboaspiration catheter AXS Catalyst 6. Methods: Patients with anterior and posterior circulation stroke were selected. Successful reperfusion defined as a Thrombolysis in Cerebral Infarction (TICI) score ≥2 b and 3-month functional independence defined as a modified Rankin Scale (mRS) ≤2 were the main efficacy outcomes. Symptomatic intracranial hemorrhage and mortality were the main safety outcomes. Results: 107 patients were suitable for analysis. Mean age was 73.18±12.62 year and median baseline NIHSS was 17 (range: 3-32). The most frequent site of occlusion was the middle cerebral artery (MCA) (60.7{\%}). 76.6{\%} of patients were treated with AXS Catalyst 6 alone without the need for rescue devices or thromboaspiration catheters. Successful reperfusion was achieved in 84.1{\%}, functional independence in 47.6{\%}, symptomatic intracranial hemorrhage occurred in 3.7{\%}, and mortality in 21.4{\%}. Conclusions: Endovascular treatment with AXS Catalyst 6 proved to be safe, technically feasible, and effective. Comparison analyses with other devices for mechanical thrombectomy are needed.",
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