Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization: European heart journal

F Crea; CN Bairey Merz; JF Beltrame; C Berry; PG Camici; JC Kaski; P Ong; CJ Pepine; U Sechtem; H Shimokawa; on behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS)

doi:10.1093/eurheartj/ehy857

Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization: European heart journal

F Crea, CN Bairey Merz, JF Beltrame, C Berry, PG Camici, JC Kaski, P Ong, CJ Pepine, U Sechtem, H Shimokawa, on behalf of the Coronary Vasomotion Disorders International Study Group (COVADIS)

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.

Original language	English
Pages (from-to)	2455-2462
Number of pages	8
Journal	European Heart Journal
Volume	40
Issue number	29
DOIs	https://doi.org/10.1093/eurheartj/ehy857
Publication status	Published - 2019

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Crea, F., Bairey Merz, CN., Beltrame, JF., Berry, C., Camici, PG., Kaski, JC., Ong, P., Pepine, CJ., Sechtem, U., Shimokawa, H., & (COVADIS), O. B. O. T. C. V. D. I. S. G. (2019). Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization: European heart journal. European Heart Journal, 40(29), 2455-2462. https://doi.org/10.1093/eurheartj/ehy857

Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization : European heart journal. / Crea, F; Bairey Merz, CN; Beltrame, JF; Berry, C; Camici, PG; Kaski, JC; Ong, P; Pepine, CJ; Sechtem, U; Shimokawa, H; (COVADIS), on behalf of the Coronary Vasomotion Disorders International Study Group.

In: European Heart Journal, Vol. 40, No. 29, 2019, p. 2455-2462.

Research output: Contribution to journal › Article

Crea, F, Bairey Merz, CN, Beltrame, JF, Berry, C, Camici, PG, Kaski, JC, Ong, P, Pepine, CJ, Sechtem, U, Shimokawa, H & (COVADIS), OBOTCVDISG 2019, 'Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization: European heart journal', European Heart Journal, vol. 40, no. 29, pp. 2455-2462. https://doi.org/10.1093/eurheartj/ehy857

Crea, F ; Bairey Merz, CN ; Beltrame, JF ; Berry, C ; Camici, PG ; Kaski, JC ; Ong, P ; Pepine, CJ ; Sechtem, U ; Shimokawa, H ; (COVADIS), on behalf of the Coronary Vasomotion Disorders International Study Group. / Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization : European heart journal. In: European Heart Journal. 2019 ; Vol. 40, No. 29. pp. 2455-2462.

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title = "Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization: European heart journal",

abstract = "Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps. Published on behalf of the European Society of Cardiology. All rights reserved. {\textcopyright} The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.",

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AU - Camici, PG

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AB - Persistence or recurrence of angina after a percutaneous coronary intervention (PCI) may affect about 20-40% of patients during short-medium-term follow-up. This appears to be true even when PCI is 'optimized' using physiology-guided approaches and drug-eluting stents. Importantly, persistent or recurrent angina post-PCI is associated with a significant economic burden. Healthcare costs may be almost two-fold higher among patients with persistent or recurrent angina post-PCI vs. those who become symptom-free. However, practice guideline recommendations regarding the management of patients with angina post-PCI are unclear. Gaps in evidence into the mechanisms of post-PCI angina are relevant, and more research seems warranted. The purpose of this document is to review potential mechanisms for the persistence or recurrence of angina post-PCI, propose a practical diagnostic algorithm, and summarize current knowledge gaps. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.

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