Abstract
Group B coxsackie viruses (CVB) readily establish persistent infections in human lymphoid cell lines. CVB3 persistence in the T cell line MOLT-4 was maintained by viral replication in a small fraction of the cells at any given time and appeared to be due to the continuous emergence of a few susceptible cells among a population of otherwise resistant cells. Chronic infection was terminated by CVB3-specific antibody and interferon (IFN). The experimental model may be useful in elucidating how CVBs are implicated in the genesis of chronic myocardiopathies.
Original language | English |
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Pages (from-to) | 441-444 |
Number of pages | 4 |
Journal | European Heart Journal |
Volume | 8 |
Issue number | SUPPL. J |
Publication status | Published - 1987 |
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine