Mediastinal images resembling thymus following 131-I treatment for thyroid cancer

Liliana Montella, M. Caraglia, A. Abbruzzese, A. Soricelli, M. Caputi, G. Squame, M. Salvatore, S. Del Prete, G. Palmieri

Research output: Contribution to journalArticlepeer-review


The follow-up of Differentiated Thyroid Cancer conventionally includes serum thyroglobulin and periodic Whole Body Scans. The uptake of 131-I in normal and pathological tissues different from metastatic thyroid cancer sites is a cause of false-positive scans. Among them, mediastinal uptake caused by thymic hyperplasia can be observed. The aim of the present study was to review a series of 573 patients with differentiated thyroid cancer treated with 131-I after surgery between 1992 and 2003 looking above all for those with mediastinal images resembling thymus. This evaluation is presented together with some hypotheses on the relationships between thymus and thyroid. Moreover, some considerations are made on the differential diagnosis between thymus and mediastinal tumour thyroid residues.

Original languageEnglish
Pages (from-to)114-117
Number of pages4
JournalMonaldi Archives for Chest Disease - Cardiac Series
Issue number2
Publication statusPublished - Jun 2005


  • 131-I therapy
  • Thymic hyperplasia
  • Thyroid cancer
  • Whole body scan

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine


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