Mediastinal irradiation in a patient affected by lung carcinoma after heart transplantation: Helical tomotherapy versus three dimensional conformal radiotherapy

Francesca M. Giugliano, Vincenzo Iorio, Fabrizio Cammarota, Diego Toledo, Rossana Senese, Ferdinando Francomacaro, Matteo Muto, Paolo Muto

Research output: Contribution to journalArticlepeer-review

Abstract

Patients who have undergone solid organ transplants are known to have an increased risk of neoplasia compared with the general population. We report our experience using mediastinal irradiation with helical tomotherapy versus three-dimensional conformal radiation therapy to treat a patient with lung carcinoma 15 years after heart transplantation. Our dosimetric evaluation showed no particular difference between the techniques, with the exception of some organs. Mediastinal irradiation after heart transplantation is feasible and should be considered after evaluation of the risk. Conformal radiotherapy or intensity-modulated radiotherapy appears to be the appropriate treatment in heart-transplanted oncologic patients.

Original languageEnglish
JournalThoracic Cancer
DOIs
Publication statusPublished - 2016

Keywords

  • Heart transplantation
  • Mediastinal irradiation
  • Tomotherapy

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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