Medical indications to antireflux surgery in gastroesophageal reflux disease

Research output: Contribution to journalArticlepeer-review


Almost all patients with severe gastroesophageal reflux disease can be effectively treated using adequate levels of antisecretory therapy. However, most patients are likely to require long-term therapy to prevent symptomatic and endoscopic relapse. Long-term proton pump inhibitor therapy is the most effective alternative to surgery; it has been shown to be both effective and safe. Antireflux surgery should be suggested in the following circumstances: a) failed medical therapy (about 10% of cases) with demonstrable symptomatic esophagitis unhealed by intensive antisecretory medication; b) medical success but at too high of a cost in young patients; c) difficult compliance with regular medication; d) patients with problematic symptoms and extraesophageal manifestations from regurgitation (asthma, laryngitis) that are not improved with antisecretory medication.

Original languageEnglish
Pages (from-to)32-33
Number of pages2
JournalGastroenterology International
Issue numberSUPPL. 2
Publication statusPublished - 1997


  • Antireflux surgery
  • GERD
  • Medical indications

ASJC Scopus subject areas

  • Gastroenterology

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