Medical prevention of recurrent acute otitis media: An updated overview

Paola Marchisio, Erica Nazzari, Sara Torretta, Susanna Esposito, Nicola Principi

Research output: Contribution to journalArticlepeer-review


Acute otitis media (AOM) is one of the most common pediatric diseases; almost all children experience at least one episode, and a third have two or more episodes in the first three years of life. The disease burden of AOM has important medical, social and economic effects. AOM requires considerable financial assistance due to needing at least one doctor visit and a prescription for antipyretics and/or antibiotics. AOM is also associated with high indirect costs, which are mostly related to lost days of work for one parent. Moreover, due to its acute symptoms and frequent recurrences, AOM considerably impacts both the child and family's quality of life. AOM prevention, particularly recurrent AOM (rAOM), is a primary goal of pediatric practice. In this paper, we review current evidence regarding the efficacy of medical treatments and vaccines for preventing rAOM and suggest the best approaches for AOM-prone children.

Original languageEnglish
Pages (from-to)611-620
Number of pages10
JournalExpert Review of Anti-Infective Therapy
Issue number5
Publication statusPublished - 2014


  • acute otitis media
  • antibiotic prophylaxis
  • complementary and alternative medicine
  • otitis media
  • prevention
  • probiotics
  • recurrent acute otitis media
  • vaccine
  • vitamin D
  • xylitol

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology
  • Virology
  • Medicine(all)


Dive into the research topics of 'Medical prevention of recurrent acute otitis media: An updated overview'. Together they form a unique fingerprint.

Cite this