La terapia medica dell'ulcera peptica: problemi e prospettive.

Translated title of the contribution: Medical therapy of peptic ulcer: problems and prospects

E. Trabucchi, D. Foschi, P. Belloli, F. Montorsi, V. Marchetti, C. Mariscotti, S. Diamantini

Research output: Contribution to journalArticlepeer-review

Abstract

In the last few years, several drugs have been proposed for the healing of peptic ulcers H2 receptor antagonists are probably the reference-drugs for their efficacy and safety. Acute treatment of peptic ulcer with cimetidine, ranitidine or famotidine gives a high healing rate: from 60% to 90%, depending on the location of the ulcer and the drug used. However, relapse after short-term treatment still remains frequent, and prophylaxis of recurrence must be decided. Long-term treatment with antisecretory drugs could be dangerous for changes of the gastric system, with nitrites and nitro-compounds occurrence, and for the risk of frequent relapses. Therefore, the role of mucus-barrier drugs and surgery must be reconsidered.

Translated title of the contributionMedical therapy of peptic ulcer: problems and prospects
Original languageItalian
Pages (from-to)1-6
Number of pages6
JournalMinerva Dietologica e Gastroenterologica
Volume35
Issue number1
Publication statusPublished - Jan 1989

ASJC Scopus subject areas

  • Medicine(all)

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