Medication adherence in hypertension

Neil R. Poulter, Claudio Borghi, Gianfranco Parati, Atul Pathak, Diana Toli, Bryan Williams, Roland E. Schmieder

Research output: Contribution to journalArticlepeer-review


: Suboptimal adherence to antihypertensive medication is a major contributor to poor blood pressure control. Several methods, direct or indirect, are available for measuring adherence, including the recently developed biochemical screening, although there is no gold-standard method routinely used in clinical practice to accurately assess the different facets of adherence. Adherence to treatment is a complex phenomenon and several of the barriers to adherence will need to be addressed at the healthcare system level; however, when looking at adherence from a more practical side and from the practitioner's perspective, the patient-practitioner relationship is a key element both in detecting adherence and in attempting to choose interventions tailored to the patient's profile. The use of single-pill combinations enabling simplification of treatment regimen, the implementation of a collaborative team-based approach and the development of electronic health tools also hold promise for improving adherence, and thus impacting cardiovascular outcomes and healthcare costs.

Original languageEnglish
Pages (from-to)579-587
Number of pages9
JournalJournal of Hypertension
Issue number4
Publication statusPublished - Apr 1 2020

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine


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