Medications for neuropathic pain: Current trends

Bruno Colombo, P. O L Annovazzi, G. Comi

Research output: Contribution to journalArticlepeer-review


Neuropathic pain is by definition a chronic pain condition that occurs and persists in a heterogeneous group of aetiologically different diseases characterised by a primary lesion or dysfunction of the peripheral or central nervous system. Neuropathic pain has an important prevalence in the general population, and a severe impact on quality of life and mood of affected patients. Therapy is based on tricyclic antidepressants and antiepileptic drugs, the most frequently studied drug classes. Opioids and analgesics are a second-line choice. Topical medications could be useful in several pain situations.

Original languageEnglish
JournalNeurological Sciences
Issue numberSUPPL. 2
Publication statusPublished - Sep 2006


  • Antidepressants
  • Antiepileptic drugs
  • Neuropathic pain
  • Opioids
  • Therapy

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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