Abstract
The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms.
| Original language | English |
|---|---|
| Pages (from-to) | 593-610 |
| Number of pages | 18 |
| Journal | Critical Reviews in Food Science and Nutrition |
| Volume | 54 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jan 2014 |
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Keywords
- Dietary pattern
- nutrition
- prevention
ASJC Scopus subject areas
- Food Science
- Industrial and Manufacturing Engineering
Cite this
Mediterranean Diet and Cardiovascular Risk Factors : A Systematic Review. / Grosso, Giuseppe; Mistretta, Antonio; Frigiola, Alessandro; Gruttadauria, Salvatore; Biondi, Antonio; Basile, Francesco; Vitaglione, Paola; D'Orazio, Nicolantonio; Galvano, Fabio.
In: Critical Reviews in Food Science and Nutrition, Vol. 54, No. 5, 01.2014, p. 593-610.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Mediterranean Diet and Cardiovascular Risk Factors
T2 - A Systematic Review
AU - Grosso, Giuseppe
AU - Mistretta, Antonio
AU - Frigiola, Alessandro
AU - Gruttadauria, Salvatore
AU - Biondi, Antonio
AU - Basile, Francesco
AU - Vitaglione, Paola
AU - D'Orazio, Nicolantonio
AU - Galvano, Fabio
PY - 2014/1
Y1 - 2014/1
N2 - The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms.
AB - The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms.
KW - Dietary pattern
KW - nutrition
KW - prevention
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UR - http://www.scopus.com/inward/citedby.url?scp=84888993854&partnerID=8YFLogxK
U2 - 10.1080/10408398.2011.596955
DO - 10.1080/10408398.2011.596955
M3 - Article
C2 - 24261534
AN - SCOPUS:84888993854
VL - 54
SP - 593
EP - 610
JO - Critical Reviews in Food Science and Nutrition
JF - Critical Reviews in Food Science and Nutrition
SN - 1040-8398
IS - 5
ER -