Mediterranean spotted fever in Lombardy: An epidemiological, clinical and laboratory study of 76 cases in the years 1977-1986

M. Tinelli, A. Maccabruni, G. Michelone, A. Zambelli

Research output: Contribution to journalArticle

Abstract

This paper describes the epidemiological, clinical and laboratory features of 76 cases of Mediterranean spotted fever occurring occurring during the years 1977-1986. The patients observed all lived in the Lombardy region of Italy, which is not located on the Mediterranean Basin. Our data show the highest prevalence of the disease, as reported by other authors, in southern regions of Italy, in the same years: 1979-1983. No differences were noted between age groups or sexes, and the late spring-summer seasonality was confirmed. The clinical signs and symptoms in our cases were those common to the disease. The microimmuno-fluorescence method was found to be more sensitive and specific than the Weil-Felix test for serological diagnosis. Finally, we showed that doxycycline and oxytetracycline both induce rapid remission of fever.

Original languageEnglish
Pages (from-to)516-520
Number of pages5
JournalEuropean Journal of Epidemiology
Volume5
Issue number4
DOIs
Publication statusPublished - Dec 1989

Fingerprint

Boutonneuse Fever
Italy
Oxytetracycline
Doxycycline
Serologic Tests
Signs and Symptoms
Fever
Age Groups
Fluorescence
Clinical Studies

Keywords

  • Epidemiology
  • Italy
  • Mediterranean spotted fever

ASJC Scopus subject areas

  • Epidemiology

Cite this

Mediterranean spotted fever in Lombardy : An epidemiological, clinical and laboratory study of 76 cases in the years 1977-1986. / Tinelli, M.; Maccabruni, A.; Michelone, G.; Zambelli, A.

In: European Journal of Epidemiology, Vol. 5, No. 4, 12.1989, p. 516-520.

Research output: Contribution to journalArticle

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