TY - JOUR
T1 - Medium-term effectiveness of L-thyroxine treatment in idiopathic dilated cardiomyopathy
AU - Moruzzi, Paolo
AU - Doria, Elisabetta
AU - Agostoni, Pier Giuseppe
PY - 1996/11
Y1 - 1996/11
N2 - BACKGROUND: In dilated cardiomyopathy, short-term administration of L-thyroxine (100 μg/ day) improves cardiac and exercise performance without changing the heart's adrenergic sensitivity. The aim of this study was to test the medium-term (3 months) efficacy of L-thyroxine (10 patients) compared with placebo (10 patients) and to find out whether later effects are obtainable. METHODS: Echocardiographic parameters in the control state and during acute changes of left ventricular after load, cardiopulmonary exercise test, and hemodynamic parameters, including cardiac β1 responses to dobutamine, were obtained before and at the end of treatment. RESULTS: Significant (P
AB - BACKGROUND: In dilated cardiomyopathy, short-term administration of L-thyroxine (100 μg/ day) improves cardiac and exercise performance without changing the heart's adrenergic sensitivity. The aim of this study was to test the medium-term (3 months) efficacy of L-thyroxine (10 patients) compared with placebo (10 patients) and to find out whether later effects are obtainable. METHODS: Echocardiographic parameters in the control state and during acute changes of left ventricular after load, cardiopulmonary exercise test, and hemodynamic parameters, including cardiac β1 responses to dobutamine, were obtained before and at the end of treatment. RESULTS: Significant (P
UR - http://www.scopus.com/inward/record.url?scp=0030281511&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030281511&partnerID=8YFLogxK
U2 - 10.1016/S0002-9343(96)00281-1
DO - 10.1016/S0002-9343(96)00281-1
M3 - Article
C2 - 8948268
AN - SCOPUS:0030281511
VL - 101
SP - 461
EP - 467
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 5
ER -