Medullary hyperplastic hematopoiesis in thalassemia: Incidental increased Tc-99m sestamibi bone marrow uptake

Giuseppe Villa, Luigi Tommasi, Barbara Colombo, Enrico Balleari

Research output: Contribution to journalArticlepeer-review

Abstract

A 62-year-old, previously healthy white man was referred to our hospital for the recent onset of lumbar pain and the presence in the serum of monoclonal IgG. Clinical workup was planned to ascertain the presence of a clinically relevant monoclonal gammopathy. Tc-99m sestamibi whole-body scintigraphy showed diffusely increased bone marrow uptake. Further laboratory tests were diagnostic for the presence of a beta-thalassemia trait with a concomitant monoclonal gammopathy of undetermined significance. The possibility of concomitant nonmalignant marrow sestamibi uptake must be considered in the clinical assessment of patients with monoclonal gammopathies.

Original languageEnglish
Pages (from-to)135-136
Number of pages2
JournalClinical Nuclear Medicine
Volume30
Issue number2
DOIs
Publication statusPublished - Feb 2005

Keywords

  • 99mTc-sestamibi
  • Bone marrow
  • Monoclonal gammopathy
  • Thalassemia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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