TY - JOUR
T1 - Medulloblastoma of the cerebellopontine angle in adulthood
AU - Magliulo, Giuseppe
AU - Parrotto, Donato
AU - Pulice, Gianna
AU - Celebrini, Alessandra
AU - Giangaspero, Felice
PY - 2005/12
Y1 - 2005/12
N2 - Cerebellar medulloblastoma is a rare malignant tumour that represents 25% of all intracranial tumours in the first 10 years of life, but only 1.1% of CNS tumours (male:female ratio 2:1) in adults. In 67-93% of the cases in childhood, medulloblastoma involves the median line of the cerebellar parenchyma. In contrast, almost 70% of the cases in adulthood are paramedian or lateral. The site of lesion may cause difficulty in reaching a diagnosis. MRI thus does not give a clear interpretation of the type of lesion. In addition, clinical medicine is not of particular help in distinguishing the various lesions that occur in the same areas. It should be stressed that the characteristics of medulloblastoma in adults are more variable than those in children and, therefore, should be included in the differential diagnosis of posterior cranial fossa lesions. We report a new case of medulloblastoma in the CPA in an adult and discuss the difficulties concerning its diagnosis and treatment.
AB - Cerebellar medulloblastoma is a rare malignant tumour that represents 25% of all intracranial tumours in the first 10 years of life, but only 1.1% of CNS tumours (male:female ratio 2:1) in adults. In 67-93% of the cases in childhood, medulloblastoma involves the median line of the cerebellar parenchyma. In contrast, almost 70% of the cases in adulthood are paramedian or lateral. The site of lesion may cause difficulty in reaching a diagnosis. MRI thus does not give a clear interpretation of the type of lesion. In addition, clinical medicine is not of particular help in distinguishing the various lesions that occur in the same areas. It should be stressed that the characteristics of medulloblastoma in adults are more variable than those in children and, therefore, should be included in the differential diagnosis of posterior cranial fossa lesions. We report a new case of medulloblastoma in the CPA in an adult and discuss the difficulties concerning its diagnosis and treatment.
KW - Acoustic neuroma
KW - Hearing loss
KW - MRI
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U2 - 10.1080/16513860500404176
DO - 10.1080/16513860500404176
M3 - Article
AN - SCOPUS:32144434070
VL - 3
SP - 208
EP - 211
JO - Audiological Medicine
JF - Audiological Medicine
SN - 1651-386X
IS - 4
ER -