Medulloblastoma variants: Age-dependent occurrence and relation to gorlin syndrome-a new clinical perspective

Maria Luisa Garrè, Armando Cama, Francesca Bagnasco, Giovanni Morana, Felice Giangaspero, Massimo Brisigotti, Claudio Gambini, Marco Forni, Andrea Rossi, Riccardo Haupt, Paolo Nozza, Salvina Barra, Gianluca Piatelli, Gian Maria Viglizzo, Valeria Capra, William Bruno, Lorenza Pastorino, Maura Massimino, Miriam Tumolo, Paola FidaniSandro Dallorso, Riccardo Fabian Schumacher, Claudia Milanaccio, Torsten Pietsch

Research output: Contribution to journalArticle

Abstract

Purpose: We aimed to test the hypothesis that medulloblastoma (MB) variants show a different age distribution and clinical behavior reflecting their specific biology, and that MB occurring at very young age is associated with cancer predisposition syndromes such as Gorlin syndrome (GS). Experimental Design: We investigated the frequency, age distribution, location, response to treatment, outcome, and association with familial cancer predisposition syndromes in a series of 82 cases of MB in patients ages

Original languageEnglish
Pages (from-to)2463-2471
Number of pages9
JournalClinical Cancer Research
Volume15
Issue number7
DOIs
Publication statusPublished - Apr 1 2009

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ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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