Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway

Simona Caporali; Ester Alvino; Adriana Amaro; Pedro Miguel Lacal; Lauretta Levati; Maria Grazia Atzori; Gian Carlo Antonini Cappellini; Federica Ruffini; Enzo Bonmassar; Ulrich Pfeffer; Stefania D'Atri

doi:10.1186/1479-5876-13-S1-P5

Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway

Simona Caporali, Ester Alvino, Adriana Amaro, Pedro Miguel Lacal, Lauretta Levati, Maria Grazia Atzori, Gian Carlo Antonini Cappellini, Federica Ruffini, Enzo Bonmassar, Ulrich Pfeffer, Stefania D'Atri

Research output: Contribution to journal › Article

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Journal of Translational Medicine
DOIs	https://doi.org/10.1186/1479-5876-13-S1-P5
Publication status	Accepted/In press - Jan 15 2015

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

Access to Document

10.1186/1479-5876-13-S1-P5

Cite this

Caporali, S., Alvino, E., Amaro, A., Lacal, P. M., Levati, L., Atzori, M. G., Cappellini, G. C. A., Ruffini, F., Bonmassar, E., Pfeffer, U., & D'Atri, S. (Accepted/In press). Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway. Journal of Translational Medicine, 1-2. https://doi.org/10.1186/1479-5876-13-S1-P5

Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway. / Caporali, Simona; Alvino, Ester; Amaro, Adriana; Lacal, Pedro Miguel; Levati, Lauretta; Atzori, Maria Grazia; Cappellini, Gian Carlo Antonini; Ruffini, Federica; Bonmassar, Enzo; Pfeffer, Ulrich ; D'Atri, Stefania.

In: Journal of Translational Medicine, 15.01.2015, p. 1-2.

Research output: Contribution to journal › Article

Caporali, S, Alvino, E, Amaro, A, Lacal, PM, Levati, L, Atzori, MG, Cappellini, GCA, Ruffini, F, Bonmassar, E, Pfeffer, U & D'Atri, S 2015, 'Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway', Journal of Translational Medicine, pp. 1-2. https://doi.org/10.1186/1479-5876-13-S1-P5

Caporali S, Alvino E, Amaro A, Lacal PM, Levati L, Atzori MG et al. Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway. Journal of Translational Medicine. 2015 Jan 15;1-2. https://doi.org/10.1186/1479-5876-13-S1-P5

Caporali, Simona ; Alvino, Ester ; Amaro, Adriana ; Lacal, Pedro Miguel ; Levati, Lauretta ; Atzori, Maria Grazia ; Cappellini, Gian Carlo Antonini ; Ruffini, Federica ; Bonmassar, Enzo ; Pfeffer, Ulrich ; D'Atri, Stefania. / Melanoma cells with acquired resistance to dabrafenib display changes in miRNA expression pattern and respond to this drug with an increase of invasiveness, which is abrogated by inhibition of NF-κB or the PI3K/mTOR signalling pathway. In: Journal of Translational Medicine. 2015 ; pp. 1-2.

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