Eight cases of vulvar melanoma, with a minimum 7 year follow-up, have been studied. One occurred in the skin and 7 were mucosal melanomas; one of these latter was incidentally found among 13 pigmented vulvar lesions. Five years survival was associated with evidence of radial growth phase, absence of anaplasia, low mitotic activity and intense host reponse. One of the 5 year survivors, with 4.1 mm thick melanoma, died from unrelated causes shortly after; the other 2, with a tumor depth of 1 mm or less, are free from disease at 7 and 12.1 years. Clark's levels in the vulva lack clinical value.
|Number of pages||13|
|Journal||Cervix and the Lower Female Genital Tract|
|Publication status||Published - 1988|
ASJC Scopus subject areas
- Obstetrics and Gynaecology