Melanoma Volatile Fingerprint with a Gas Sensor Array: In Vivo and In Vitro Study

G. Pennazza, M. Santonico, A. Bartolazzi, [No Value] Martinelli, R. Paolesse, C. Di Natale, R. Bono, V. Tamburrelli, S. Cristina, A. D'Amico

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Volatile compounds fingerprinting with gas sensor arrays is a promising non-invasive methodology for human health-state monitoring. Anyway, the large variability of human samples (breath, urine, sweat, skin transpiration) may have a complex influence in the composition of the volatile part and in the reproducibility of the analyses. Nonetheless, skin analysis is a favourable application where each subject can provide its own reference: free skin portions compared with skin lesions, avoiding the masking effects of skin volatiles composition variability. Moreover, in vitro measurements of melanoma cell lines show that enough information to recognize different tumor-types can be obtained by cells headspace.

Original languageEnglish
Title of host publicationProcedia Chemistry
Pages995-998
Number of pages4
Volume1
Edition1
DOIs
Publication statusPublished - Sep 2009
EventEurosensors 23rd Conference - Lausanne, Switzerland
Duration: Sep 6 2009Sep 9 2009

Other

OtherEurosensors 23rd Conference
CountrySwitzerland
CityLausanne
Period9/6/099/9/09

Keywords

  • Cell headspace
  • Gas sensor array
  • Melanoma
  • Non-invasive diagnosis
  • Volatile compounds fingerprinting

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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