Abstract
A fall in nocturnal plasma melatonin occurs in patients with cluster headache, suggesting that melatonin may play a role in the promotion of attacks. During a cluster period, we administered melatonin to 20 cluster headache patients (2 primary chronic, 18 episodic) in a double-blind placebo-controlled study of oral melatonin 10 mg (n=10) or placebo (n=10) for 14 days taken in a single evening dose. Headache frequency was significantly reduced (ANOVA, p
| Original language | English |
|---|---|
| Pages (from-to) | 494-496 |
| Number of pages | 3 |
| Journal | Cephalalgia |
| Volume | 16 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1996 |
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Keywords
- Cluster headache
- Melatonin
- Pathogenesis
- Prophylaxis
ASJC Scopus subject areas
- Clinical Neurology
Cite this
Melatonin versus placebo in the prophylaxis of cluster headache : A double-blind pilot study with parallel groups. / Leone, M.; D'Amico, D.; Moschiano, F.; Fraschini, F.; Bussone, G.
In: Cephalalgia, Vol. 16, No. 7, 1996, p. 494-496.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Melatonin versus placebo in the prophylaxis of cluster headache
T2 - A double-blind pilot study with parallel groups
AU - Leone, M.
AU - D'Amico, D.
AU - Moschiano, F.
AU - Fraschini, F.
AU - Bussone, G.
PY - 1996
Y1 - 1996
N2 - A fall in nocturnal plasma melatonin occurs in patients with cluster headache, suggesting that melatonin may play a role in the promotion of attacks. During a cluster period, we administered melatonin to 20 cluster headache patients (2 primary chronic, 18 episodic) in a double-blind placebo-controlled study of oral melatonin 10 mg (n=10) or placebo (n=10) for 14 days taken in a single evening dose. Headache frequency was significantly reduced (ANOVA, p
AB - A fall in nocturnal plasma melatonin occurs in patients with cluster headache, suggesting that melatonin may play a role in the promotion of attacks. During a cluster period, we administered melatonin to 20 cluster headache patients (2 primary chronic, 18 episodic) in a double-blind placebo-controlled study of oral melatonin 10 mg (n=10) or placebo (n=10) for 14 days taken in a single evening dose. Headache frequency was significantly reduced (ANOVA, p
KW - Cluster headache
KW - Melatonin
KW - Pathogenesis
KW - Prophylaxis
UR - http://www.scopus.com/inward/record.url?scp=0029827884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029827884&partnerID=8YFLogxK
U2 - 10.1046/j.1468-2982.1996.1607494.x
DO - 10.1046/j.1468-2982.1996.1607494.x
M3 - Article
C2 - 8933994
AN - SCOPUS:0029827884
VL - 16
SP - 494
EP - 496
JO - Cephalalgia
JF - Cephalalgia
SN - 0333-1024
IS - 7
ER -