Abstract
A fall in nocturnal plasma melatonin occurs in patients with cluster headache, suggesting that melatonin may play a role in the promotion of attacks. During a cluster period, we administered melatonin to 20 cluster headache patients (2 primary chronic, 18 episodic) in a double-blind placebo-controlled study of oral melatonin 10 mg (n=10) or placebo (n=10) for 14 days taken in a single evening dose. Headache frequency was significantly reduced (ANOVA, p
Original language | English |
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Pages (from-to) | 494-496 |
Number of pages | 3 |
Journal | Cephalalgia |
Volume | 16 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1996 |
Keywords
- Cluster headache
- Melatonin
- Pathogenesis
- Prophylaxis
ASJC Scopus subject areas
- Clinical Neurology