Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

Research output: Contribution to journalShort surveypeer-review

Abstract

The pro-tumoral diversion of macrophages remains an unresolved paradox of tumor immunology and a conceptual gap in the understanding of tumor biology. Goossens et al. (2019) identify a new level of cross-regulation by which tumors increase the membrane cholesterol efflux of macrophages to enhance their pro-tumoral activation in response to IL-4.

Original languageEnglish
Pages (from-to)1238-1240
Number of pages3
JournalCell Metabolism
Volume29
Issue number6
DOIs
Publication statusPublished - Jun 4 2019

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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