Memory disturbances and temporal lobe epilepsy simulating Alzheimer's disease: A case report

Elena Sinforiani, Raffaele Manni, Luca Bernasconi, Lara Maria Banchieri, Chiara Zucchella

Research output: Contribution to journalArticlepeer-review

Abstract

We report the case of a patient presenting with recurrent transient dyscognitive episodes and memory disturbances, simulating the clinical picture of early Alzheimer's disease (AD). Neuropsychological examination showed only episodic memory impairment without significant progression over time in the absence of any other cognitive dysfunctions; magnetic resonance imaging failed to show selective temporal atrophy. The suspicion that a nocturnal epileptic seizure had occurred arose on the basis of a clinical report of tongue biting and the findings of sharp waves over the temporal region on standard EEC. Thus 600 mg/day of carbamazepine was added to donezepil therapy. Antiepileptic treatment completely reversed the cognitive disturbances. Our observation stresses the possibility that unrecognised epilepsy may present as early AD.

Original languageEnglish
Pages (from-to)39-41
Number of pages3
JournalFunctional Neurology
Volume18
Issue number1
Publication statusPublished - Jan 2003

Keywords

  • Alzheimer's disease
  • Epilepsy
  • Memory impairment
  • MRI
  • Neuropsychological evaluation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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