Abstract
From a group of 20 patients studied in our center from 1988 to 1993 we drew out 5 patients that collect most of signs and symptoms of meningeal carcinomatosis. Each patient, excepting case 5, was given Methotrexate (MTX), 10 mg/m2 weekly intrathecally by lumbar puncture until the results of CSF cytodiagnosis were negative. Patients 5 was treated, without benefit, only with whole brain radiotherapy. One patient had a lung cancer, the others had breast adc. In this group of patients the utility of MTX administered intrathecally by lumbar puncture is confirmed. The treatment improves or stabilizes neurological symptomatology and at times prolongs survival of patients.
| Original language | Italian |
|---|---|
| Pages (from-to) | 671-675 |
| Number of pages | 5 |
| Journal | Rivista di Neurobiologia |
| Volume | 41 |
| Issue number | 5 |
| Publication status | Published - 1995 |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Pietrangeli, A., Bove, L., Innocenti, P., Pace, A., & Jandolo, B. (1995). MENINGITI CARCINOMATOSE: ASPETTI CLINICI E DECORSO IN 5 PAZIENTI TRATTATI CON METOTREXATE ENDORACHIDE. Rivista di Neurobiologia, 41(5), 671-675.