Meningeal hemangiopericytoma only diagnosed at the time of late bone metastasis

Kantang Satayasoontorn, Alberto Righi, Marco Gambarotti, Biagio Merlino, Eugenio Brunocilla, Daniel Vanel

Research output: Contribution to journalArticlepeer-review

Abstract

Hemangiopericytoma is a rare neoplasm. Primary meningeal hemangiopericytomas account for 1 to 7 % of all meningeal tumors. In the literature, meningeal hemangiopericytomas are mainly case reports, which confirm an aggressive behavior with a high rate of local recurrence and extracranial metastasis. Metastasis can be seen many years after initial surgical excision of the primary tumor, and the most common sites include the bone, liver and lung. We present a pathological study of four meningeal hemangiopericytomas with bone metastases. All patients are male with a mean age of 46.5 years. Metastases only involved bone. Three out of four lesions were initially misdiagnosed as meningiomas. Only one case was initially correctly diagnosed as meningeal hemangiopericytoma. All patients underwent surgery with complete resection. Only the patient immediately diagnosed with meningeal hemangiopericytoma received postoperative radiation therapy. Three patients had bone metastases without local recurrence including the one who received radiation therapy. One patient recurred locally after 7 years, and bone metastasis was found at the same time. Our cases confirm that meningeal hemangiopericytomas are a separate entity and have a high recurrence rate despite complete surgical resection, with extracranial metastases, mainly to bone, even after long intervals.

Original languageEnglish
Pages (from-to)1543-1549
Number of pages7
JournalSkeletal Radiology
Volume43
Issue number11
DOIs
Publication statusPublished - 2014

Keywords

  • Meningeal hemangiopericytoma
  • Meningioma
  • Misdiagnosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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