Meningioma with meningioangiomatosis

A condition mimicking invasive meningiomas in children and young adults: Report of two cases and review of the literature

Felice Giangaspero, Antonio Guiducci, Frederick A. Lenz, Luciano Mastronardi, Peter C. Burger

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Meningioangiomatosis is a malformative meningovascular proliferation that occurs sporadically and in patients with neurofibromatosis type 2. Its histologic features of perivascular proliferation of elongated fibroblast and meningothelial cells trapping islands of gliotic cortex may be erroneously interpreted as invasion when an overlying meningioma is present. We report two cases of meningioangiomatosis associated with meningioma and review the literature on the subject for a total of six cases. The age of patients ranged from 9 months to 33 years. All cases were single lesions, and none had clinical evidence of neurofibromatosis type 2. Meningiomas in children have been regarded as having more aggressive behavior than their adult counterparts, with more frequent invasion of the underlying brain. The lack of correlation between brain invasion and recurrence observed in series of meningiomas in young patients may suggest that some of these lesions are meningioangiomatosis associated with meningioma rather than invasive meningiomas.

Original languageEnglish
Pages (from-to)872-875
Number of pages4
JournalAmerican Journal of Surgical Pathology
Volume23
Issue number8
DOIs
Publication statusPublished - Aug 1999

Fingerprint

Meningioma
Young Adult
Neurofibromatosis 2
Brain
Islands
Fibroblasts
Recurrence

Keywords

  • Meningioangiomatosis
  • Meningioma
  • Neurofibromatosis type 2

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine

Cite this

Meningioma with meningioangiomatosis : A condition mimicking invasive meningiomas in children and young adults: Report of two cases and review of the literature. / Giangaspero, Felice; Guiducci, Antonio; Lenz, Frederick A.; Mastronardi, Luciano; Burger, Peter C.

In: American Journal of Surgical Pathology, Vol. 23, No. 8, 08.1999, p. 872-875.

Research output: Contribution to journalArticle

@article{276538eb984a45619f1aa3c2d24836ba,
title = "Meningioma with meningioangiomatosis: A condition mimicking invasive meningiomas in children and young adults: Report of two cases and review of the literature",
abstract = "Meningioangiomatosis is a malformative meningovascular proliferation that occurs sporadically and in patients with neurofibromatosis type 2. Its histologic features of perivascular proliferation of elongated fibroblast and meningothelial cells trapping islands of gliotic cortex may be erroneously interpreted as invasion when an overlying meningioma is present. We report two cases of meningioangiomatosis associated with meningioma and review the literature on the subject for a total of six cases. The age of patients ranged from 9 months to 33 years. All cases were single lesions, and none had clinical evidence of neurofibromatosis type 2. Meningiomas in children have been regarded as having more aggressive behavior than their adult counterparts, with more frequent invasion of the underlying brain. The lack of correlation between brain invasion and recurrence observed in series of meningiomas in young patients may suggest that some of these lesions are meningioangiomatosis associated with meningioma rather than invasive meningiomas.",
keywords = "Meningioangiomatosis, Meningioma, Neurofibromatosis type 2",
author = "Felice Giangaspero and Antonio Guiducci and Lenz, {Frederick A.} and Luciano Mastronardi and Burger, {Peter C.}",
year = "1999",
month = "8",
doi = "10.1097/00000478-199908000-00002",
language = "English",
volume = "23",
pages = "872--875",
journal = "American Journal of Surgical Pathology",
issn = "0147-5185",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

TY - JOUR

T1 - Meningioma with meningioangiomatosis

T2 - A condition mimicking invasive meningiomas in children and young adults: Report of two cases and review of the literature

AU - Giangaspero, Felice

AU - Guiducci, Antonio

AU - Lenz, Frederick A.

AU - Mastronardi, Luciano

AU - Burger, Peter C.

PY - 1999/8

Y1 - 1999/8

N2 - Meningioangiomatosis is a malformative meningovascular proliferation that occurs sporadically and in patients with neurofibromatosis type 2. Its histologic features of perivascular proliferation of elongated fibroblast and meningothelial cells trapping islands of gliotic cortex may be erroneously interpreted as invasion when an overlying meningioma is present. We report two cases of meningioangiomatosis associated with meningioma and review the literature on the subject for a total of six cases. The age of patients ranged from 9 months to 33 years. All cases were single lesions, and none had clinical evidence of neurofibromatosis type 2. Meningiomas in children have been regarded as having more aggressive behavior than their adult counterparts, with more frequent invasion of the underlying brain. The lack of correlation between brain invasion and recurrence observed in series of meningiomas in young patients may suggest that some of these lesions are meningioangiomatosis associated with meningioma rather than invasive meningiomas.

AB - Meningioangiomatosis is a malformative meningovascular proliferation that occurs sporadically and in patients with neurofibromatosis type 2. Its histologic features of perivascular proliferation of elongated fibroblast and meningothelial cells trapping islands of gliotic cortex may be erroneously interpreted as invasion when an overlying meningioma is present. We report two cases of meningioangiomatosis associated with meningioma and review the literature on the subject for a total of six cases. The age of patients ranged from 9 months to 33 years. All cases were single lesions, and none had clinical evidence of neurofibromatosis type 2. Meningiomas in children have been regarded as having more aggressive behavior than their adult counterparts, with more frequent invasion of the underlying brain. The lack of correlation between brain invasion and recurrence observed in series of meningiomas in young patients may suggest that some of these lesions are meningioangiomatosis associated with meningioma rather than invasive meningiomas.

KW - Meningioangiomatosis

KW - Meningioma

KW - Neurofibromatosis type 2

UR - http://www.scopus.com/inward/record.url?scp=0032813557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032813557&partnerID=8YFLogxK

U2 - 10.1097/00000478-199908000-00002

DO - 10.1097/00000478-199908000-00002

M3 - Article

VL - 23

SP - 872

EP - 875

JO - American Journal of Surgical Pathology

JF - American Journal of Surgical Pathology

SN - 0147-5185

IS - 8

ER -