Meningiomas of meckel's cave

Roberto Delfini, Gualtiero Innocenzi, Pasquale Ciappetta, Maurizio Domenicucci, Giampaolo Cantore

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A SERIES OF 16 patients with meningiomas of Meckel's cave is reported. Trigeminal neuralgia, typical or atypical, was the initial symptom in 10 patients (62.5%). At admission, trigeminal signs and symptoms were present in 15 patients (93.7%); in 7 patients (43.7%), trigeminal dysfunction was combined with the impairment of other cranial nerves. On retrospective analysis, these patients fall into two clinical groups that differ also in prognosis. Group 1 comprises eight patients with trigeminal signs and symptoms only. These patients had small meningiomas strictly affecting Meckel's cave. Total removal of the tumor was achieved in seven of eight patients, without adjunctive postoperative neurological deficits. In this group, there were no tumor recurrences. Group 2 comprises the other eight patients in whom trigeminal dysfunction was combined with impairment of other cranial nerves. These patients had large tumors arising from Meckel's cave and secondarily invading the cavernous sinus (five patients) or extending into the posterior fossa (two patients) or largely growing into the middle fossa (one patient). Total removal was achieved in only one patient, and a worsening of the preoperative neurological status was observed in four patients; there were three cases of tumor progression. A subtemporal intradural approach (used in the past in every case) is still used for the small tumors of Group 1 with good results. Since 1985, for tumors involving the cavernous sinus, we have employed a frontotemporal craniotomy with extradural clinoidectomy and superior and lateral approach to the cavernous sinus. When the tumor extends toward the posterior fossa, we use a combined temporosuboccipital-transpetrosal approach. These new surgical approaches allow a better exposure of the Meckel's cave lesions and the adjacent neurovascular structures–with encouraging results.

Original languageEnglish
Pages (from-to)1000-1007
Number of pages8
JournalNeurosurgery
Volume31
Issue number6
Publication statusPublished - 1992

Fingerprint

Meningioma
Cavernous Sinus
Neoplasms
Cranial Nerves
Signs and Symptoms
Trigeminal Neuralgia
Craniotomy

Keywords

  • Cavernous sinus
  • Meckel's cave tumors
  • Meningiomas
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Delfini, R., Innocenzi, G., Ciappetta, P., Domenicucci, M., & Cantore, G. (1992). Meningiomas of meckel's cave. Neurosurgery, 31(6), 1000-1007.

Meningiomas of meckel's cave. / Delfini, Roberto; Innocenzi, Gualtiero; Ciappetta, Pasquale; Domenicucci, Maurizio; Cantore, Giampaolo.

In: Neurosurgery, Vol. 31, No. 6, 1992, p. 1000-1007.

Research output: Contribution to journalArticle

Delfini, R, Innocenzi, G, Ciappetta, P, Domenicucci, M & Cantore, G 1992, 'Meningiomas of meckel's cave', Neurosurgery, vol. 31, no. 6, pp. 1000-1007.
Delfini R, Innocenzi G, Ciappetta P, Domenicucci M, Cantore G. Meningiomas of meckel's cave. Neurosurgery. 1992;31(6):1000-1007.
Delfini, Roberto ; Innocenzi, Gualtiero ; Ciappetta, Pasquale ; Domenicucci, Maurizio ; Cantore, Giampaolo. / Meningiomas of meckel's cave. In: Neurosurgery. 1992 ; Vol. 31, No. 6. pp. 1000-1007.
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