Menstrual and reproductive factors and pancreatic cancer risk in women

E. Fernandez, C. La Vecchia, B. D'Avanzo, E. Negri

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

To investigate possible correlates of the systematically higher pancreatic cancer rates in males than in females, the role of menstrual, reproductive and hormonal factors in females have been assessed using data from a case-control study conducted in Northern Italy. Cases were 133 women with histologically confirmed incident cancer of the pancreas, and controls were 377 women in hospital for acute, non-neoplastic, non-digestive-tract disorders. After allowance for age, education, area of residence and smoking habit, an increased risk of pancreatic cancer was observed in women with early menarche (≤13 years) (OR = 1.9; 95% CI: 1.0-3.6), but no significant association was observed with age at menopause or length of fertile life. Parous women were at reduced risk as compared to nulliparous women (OR = 0.7), although the trend in risk with number of births was not significant, No association with spontaneous or induced abortions was observed. Pancreatic cancer risk was inversely related to early age at first birth (first birth

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalInternational Journal of Cancer
Volume62
Issue number1
DOIs
Publication statusPublished - 1995

Fingerprint

Pancreatic Neoplasms
Birth Order
Menarche
Induced Abortion
Spontaneous Abortion
Menopause
Italy
Habits
Case-Control Studies
Smoking
Parturition
Education

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Menstrual and reproductive factors and pancreatic cancer risk in women. / Fernandez, E.; La Vecchia, C.; D'Avanzo, B.; Negri, E.

In: International Journal of Cancer, Vol. 62, No. 1, 1995, p. 11-14.

Research output: Contribution to journalArticle

Fernandez, E. ; La Vecchia, C. ; D'Avanzo, B. ; Negri, E. / Menstrual and reproductive factors and pancreatic cancer risk in women. In: International Journal of Cancer. 1995 ; Vol. 62, No. 1. pp. 11-14.
@article{a8ca9dc02789494da46376099dc6c057,
title = "Menstrual and reproductive factors and pancreatic cancer risk in women",
abstract = "To investigate possible correlates of the systematically higher pancreatic cancer rates in males than in females, the role of menstrual, reproductive and hormonal factors in females have been assessed using data from a case-control study conducted in Northern Italy. Cases were 133 women with histologically confirmed incident cancer of the pancreas, and controls were 377 women in hospital for acute, non-neoplastic, non-digestive-tract disorders. After allowance for age, education, area of residence and smoking habit, an increased risk of pancreatic cancer was observed in women with early menarche (≤13 years) (OR = 1.9; 95{\%} CI: 1.0-3.6), but no significant association was observed with age at menopause or length of fertile life. Parous women were at reduced risk as compared to nulliparous women (OR = 0.7), although the trend in risk with number of births was not significant, No association with spontaneous or induced abortions was observed. Pancreatic cancer risk was inversely related to early age at first birth (first birth",
author = "E. Fernandez and {La Vecchia}, C. and B. D'Avanzo and E. Negri",
year = "1995",
doi = "10.1002/ijc.2910620104",
language = "English",
volume = "62",
pages = "11--14",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Menstrual and reproductive factors and pancreatic cancer risk in women

AU - Fernandez, E.

AU - La Vecchia, C.

AU - D'Avanzo, B.

AU - Negri, E.

PY - 1995

Y1 - 1995

N2 - To investigate possible correlates of the systematically higher pancreatic cancer rates in males than in females, the role of menstrual, reproductive and hormonal factors in females have been assessed using data from a case-control study conducted in Northern Italy. Cases were 133 women with histologically confirmed incident cancer of the pancreas, and controls were 377 women in hospital for acute, non-neoplastic, non-digestive-tract disorders. After allowance for age, education, area of residence and smoking habit, an increased risk of pancreatic cancer was observed in women with early menarche (≤13 years) (OR = 1.9; 95% CI: 1.0-3.6), but no significant association was observed with age at menopause or length of fertile life. Parous women were at reduced risk as compared to nulliparous women (OR = 0.7), although the trend in risk with number of births was not significant, No association with spontaneous or induced abortions was observed. Pancreatic cancer risk was inversely related to early age at first birth (first birth

AB - To investigate possible correlates of the systematically higher pancreatic cancer rates in males than in females, the role of menstrual, reproductive and hormonal factors in females have been assessed using data from a case-control study conducted in Northern Italy. Cases were 133 women with histologically confirmed incident cancer of the pancreas, and controls were 377 women in hospital for acute, non-neoplastic, non-digestive-tract disorders. After allowance for age, education, area of residence and smoking habit, an increased risk of pancreatic cancer was observed in women with early menarche (≤13 years) (OR = 1.9; 95% CI: 1.0-3.6), but no significant association was observed with age at menopause or length of fertile life. Parous women were at reduced risk as compared to nulliparous women (OR = 0.7), although the trend in risk with number of births was not significant, No association with spontaneous or induced abortions was observed. Pancreatic cancer risk was inversely related to early age at first birth (first birth

UR - http://www.scopus.com/inward/record.url?scp=0029046074&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029046074&partnerID=8YFLogxK

U2 - 10.1002/ijc.2910620104

DO - 10.1002/ijc.2910620104

M3 - Article

C2 - 7601558

AN - SCOPUS:0029046074

VL - 62

SP - 11

EP - 14

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 1

ER -