Menstrual cycle-related sensitivity to 35% CO2 in panic patients

Giampaolo Perna, Francesca Brambilla, Cinzia Arancio, Laura Bellodi

Research output: Contribution to journalArticlepeer-review


In a double blind, random, cross-over design, 10 patients and seven controls inhaled one vital capacity of 35% CO2-65% O2 during their early-follicular and midluteal phases. Anxiety after CO2 intake was significantly stronger in the early-follicular phase than in the midluteal phase for patients. Controls had no anxiety reactions.

Original languageEnglish
Pages (from-to)528-532
Number of pages5
JournalBiological Psychiatry
Issue number8
Publication statusPublished - Apr 15 1995


  • CO
  • panic
  • Sex hormones

ASJC Scopus subject areas

  • Biological Psychiatry


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