Merkel cell Carcinoma arising on a pre-existing Bowen's disease

Is it just by chance?

Alice Casari, Giuseppe Argenziano, Simonetta Piana, Aimilios Lallas, Elvira Moscarella, Mara Lombardi, Margherita Raucci, Giovanni Pellacani, Caterina Longo

Research output: Contribution to journalArticle

Abstract

Merkel cell Carcinoma (MCC) is a cutaneous Carcinoma with neuroendocrine differentiation. It arises typically on sun-exposed areas of elderly men as an asymptomatic, rapidly growing, red nodule. Although it is usually found as a solitary nodule, in almost one third of cases MCC may be associated with other malignancies such as basal cell or squamous cell carcinomas. Merkel cell Carcinoma should be considered as differential diagnosis every time we have a rapidly growing, red nodule, arising in an elderly patient with signs of sun-damage. We report a case of MCC developing in association with a pre-existing Bowen's disease. The association between MCC and Bowen's disease is quite common and their area of occurrence is usually a sun-exposed area. Ultraviolet radiation contributes to the etiology of both the malignancies.

Original languageEnglish
Pages (from-to)273-275
Number of pages3
JournalGiornale Italiano di Dermatologia e Venereologia
Volume153
Issue number2
DOIs
Publication statusPublished - Apr 1 2018

Fingerprint

Bowen's Disease
Merkel Cell Carcinoma
Preexisting Condition Coverage
Solar System
Neuroendocrine Carcinoma
Squamous Cell Carcinoma
Neoplasms
Differential Diagnosis
Radiation
Skin

Keywords

  • Bowen's disease
  • Carcinoma
  • Merkel cell
  • Ultraviolet rays

ASJC Scopus subject areas

  • Dermatology

Cite this

Merkel cell Carcinoma arising on a pre-existing Bowen's disease : Is it just by chance? / Casari, Alice; Argenziano, Giuseppe; Piana, Simonetta; Lallas, Aimilios; Moscarella, Elvira; Lombardi, Mara; Raucci, Margherita; Pellacani, Giovanni; Longo, Caterina.

In: Giornale Italiano di Dermatologia e Venereologia, Vol. 153, No. 2, 01.04.2018, p. 273-275.

Research output: Contribution to journalArticle

Casari, Alice ; Argenziano, Giuseppe ; Piana, Simonetta ; Lallas, Aimilios ; Moscarella, Elvira ; Lombardi, Mara ; Raucci, Margherita ; Pellacani, Giovanni ; Longo, Caterina. / Merkel cell Carcinoma arising on a pre-existing Bowen's disease : Is it just by chance?. In: Giornale Italiano di Dermatologia e Venereologia. 2018 ; Vol. 153, No. 2. pp. 273-275.
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