Abstract
Merkel cell Carcinoma (MCC) is a cutaneous Carcinoma with neuroendocrine differentiation. It arises typically on sun-exposed areas of elderly men as an asymptomatic, rapidly growing, red nodule. Although it is usually found as a solitary nodule, in almost one third of cases MCC may be associated with other malignancies such as basal cell or squamous cell carcinomas. Merkel cell Carcinoma should be considered as differential diagnosis every time we have a rapidly growing, red nodule, arising in an elderly patient with signs of sun-damage. We report a case of MCC developing in association with a pre-existing Bowen's disease. The association between MCC and Bowen's disease is quite common and their area of occurrence is usually a sun-exposed area. Ultraviolet radiation contributes to the etiology of both the malignancies.
| Original language | English |
|---|---|
| Pages (from-to) | 273-275 |
| Number of pages | 3 |
| Journal | Giornale Italiano di Dermatologia e Venereologia |
| Volume | 153 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2018 |
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Keywords
- Bowen's disease
- Carcinoma
- Merkel cell
- Ultraviolet rays
ASJC Scopus subject areas
- Dermatology
Cite this
Merkel cell Carcinoma arising on a pre-existing Bowen's disease : Is it just by chance? / Casari, Alice; Argenziano, Giuseppe; Piana, Simonetta; Lallas, Aimilios; Moscarella, Elvira; Lombardi, Mara; Raucci, Margherita; Pellacani, Giovanni; Longo, Caterina.
In: Giornale Italiano di Dermatologia e Venereologia, Vol. 153, No. 2, 01.04.2018, p. 273-275.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Merkel cell Carcinoma arising on a pre-existing Bowen's disease
T2 - Is it just by chance?
AU - Casari, Alice
AU - Argenziano, Giuseppe
AU - Piana, Simonetta
AU - Lallas, Aimilios
AU - Moscarella, Elvira
AU - Lombardi, Mara
AU - Raucci, Margherita
AU - Pellacani, Giovanni
AU - Longo, Caterina
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Merkel cell Carcinoma (MCC) is a cutaneous Carcinoma with neuroendocrine differentiation. It arises typically on sun-exposed areas of elderly men as an asymptomatic, rapidly growing, red nodule. Although it is usually found as a solitary nodule, in almost one third of cases MCC may be associated with other malignancies such as basal cell or squamous cell carcinomas. Merkel cell Carcinoma should be considered as differential diagnosis every time we have a rapidly growing, red nodule, arising in an elderly patient with signs of sun-damage. We report a case of MCC developing in association with a pre-existing Bowen's disease. The association between MCC and Bowen's disease is quite common and their area of occurrence is usually a sun-exposed area. Ultraviolet radiation contributes to the etiology of both the malignancies.
AB - Merkel cell Carcinoma (MCC) is a cutaneous Carcinoma with neuroendocrine differentiation. It arises typically on sun-exposed areas of elderly men as an asymptomatic, rapidly growing, red nodule. Although it is usually found as a solitary nodule, in almost one third of cases MCC may be associated with other malignancies such as basal cell or squamous cell carcinomas. Merkel cell Carcinoma should be considered as differential diagnosis every time we have a rapidly growing, red nodule, arising in an elderly patient with signs of sun-damage. We report a case of MCC developing in association with a pre-existing Bowen's disease. The association between MCC and Bowen's disease is quite common and their area of occurrence is usually a sun-exposed area. Ultraviolet radiation contributes to the etiology of both the malignancies.
KW - Bowen's disease
KW - Carcinoma
KW - Merkel cell
KW - Ultraviolet rays
UR - http://www.scopus.com/inward/record.url?scp=85044512052&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044512052&partnerID=8YFLogxK
U2 - 10.23736/S0392-0488.17.04987-2
DO - 10.23736/S0392-0488.17.04987-2
M3 - Article
VL - 153
SP - 273
EP - 275
JO - Minerva dermatologica
JF - Minerva dermatologica
SN - 0392-0488
IS - 2
ER -